|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant Epstein-Barr virus (Herpesvirus 4) EBV Glycoprotein gp350/EBV GP350 Protein|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Epstein-Barr virus (Herpesvirus 4) EBV Glycoprotein gp350/EBV GP350.
Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EBV gp350
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