Hs00472618_cn

• Gene Symbol: CPSF3L
• Assay Reference Genome Location: Chr.1:1320472 on build GRCh38
• Cytoband: 1p36.33

Target Gene Details

• Entrez Gene ID: 54973
• Gene Name: cleavage and polyadenylation specific factor 3-like
• Gene Aliases: CPSF73L, INT11, INTS11, RC-68, RC68
• Location: Chr.1:1311585-1324687 on Build GRCh38
• Assay Gene Location: Overlaps Intron 5 - Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CPSF3L	NM_001256456.1			NP_001243385.1
	NM_001256460.1			NP_001243389.1
	NM_001256462.1			NP_001243391.1
	NM_001256463.1			NP_001243392.1
	NM_017871.5			NP_060341.2
	XM_011541647.1			XP_011539949.1
	XM_011541648.1			XP_011539950.1
	XM_011541650.1			XP_011539952.1
	XM_017001557.1			XP_016857046.1
	XM_017001558.1			XP_016857047.1
	AK021939.1			BAB13943.1
	AK022675.1	2	653
	AK023356.1			BAB14541.1
	AK027767.1
	AK056652.1
	AK058018.1
	AK092190.1
	AK291387.1
	AK297350.1
	AL136813.1			CAB66747.1
	BC007978.2			AAH07978.1
	BC008041.2			AAH08041.1
	BC020199.1			AAH20199.1
	CR533557.1			CAG38588.1
	DC295791.1
	DC299237.1
	DC299993.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv482937	Chr.1:10001 - 2368561 on Build GRCh38	Loss	CCNL2 NADK DDX11L1 ISG15 LOC100130417 SLC35E2B FAM87B LOC148413 TNFRSF18 TTLL10 TMEM88B CALML6 KLHL17 FAM41C MIR6723 UBE2J2 PERM1 PLEKHN1 LINC00115 SDF4 FAM132A LOC102724312 LOC100288069 FAM138A OR4F16 MIR200B RNF223 TTLL10-AS1 LOC729737 C1orf159 AURKAIP1 LINC01128 MIR6859-2 MIB2 B3GALT6 CPSF3L MIR6727 MMP23B MORN1 SSU72 LOC107985728 HES4 LOC101928626 LOC100287934 SAMD11 PRKCZ FNDC10 OR4F5 ATAD3B MIR1302-2 GNB1 CPTP LOC105378948 MXRA8 LOC100506504 LOC284600 MTND1P23 CDK11A TAS1R3 PUSL1 TNFRSF4 TMEM52 MRPL20 MIR6808 CFAP74 DVL1 LOC105378589 LOC100129534 ATAD3A LOC102725121 MIR200A SKI LOC105378947 MMP23A LOC100132287 ACAP3 OR4F29 MIR429 SLC35E2 LOC105378592 FAAP20 AGRN LOC105378949 GABRD LOC105378591 ATAD3C VWA1 NOC2L MTND2P28 LOC100288175 LOC100134822 LOC100133331 ANKRD65 SCNN1D MIR6859-1 WASH7P LINC01342 LOC107984841 TMEM240 LOC107985729 MIR6726 CDK11B
nsv544971	Chr.1:1294063 - 1351426 on Build GRCh38	Loss	MIR6726 CPSF3L MIR6727 CPTP TAS1R3 PUSL1 ACAP3 MIR6808 DVL1
nsv544969	Chr.1:1290683 - 1374597 on Build GRCh38	Loss	MIR6726 CPSF3L MIR6727 CPTP SCNN1D TAS1R3 MXRA8 PUSL1 ACAP3 MIR6808 AURKAIP1 DVL1
nsv997291	Chr.1:1306835 - 1376336 on Build GRCh38	Gain	CPSF3L MIR6727 CPTP TAS1R3 MXRA8 PUSL1 ACAP3 MIR6808 AURKAIP1 DVL1
nsv470680	Chr.1:1070426 - 1378635 on Build GRCh38	Loss	MIR429 MIR200B RNF223 TTLL10-AS1 CPTP MXRA8 TAS1R3 C1orf159 PUSL1 TNFRSF18 TNFRSF4 MIR6808 TTLL10 AURKAIP1 DVL1 B3GALT6 CPSF3L MIR6727 SCNN1D MIR200A LINC01342 UBE2J2 MIR6726 ACAP3 SDF4 FAM132A
dgv6n100	Chr.1:1301750 - 1362354 on Build GRCh38	Gain+Loss	CPSF3L MIR6727 CPTP TAS1R3 MXRA8 PUSL1 ACAP3 MIR6808 DVL1
esv3584992	Chr.1:1314419 - 1330342 on Build GRCh38	Gain	CPSF3L CPTP
nsv1160788	Chr.1:1282706 - 1376336 on Build GRCh38	Deletion	MIR6726 CPSF3L MIR6727 CPTP SCNN1D TAS1R3 MXRA8 PUSL1 ACAP3 MIR6808 AURKAIP1 DVL1
nsv1160772	Chr.1:1027585 - 1333467 on Build GRCh38	Duplication	MIR429 MIR200B RNF223 TTLL10-AS1 CPTP LOC105378948 AGRN TAS1R3 LOC100288175 C1orf159 PUSL1 TNFRSF18 TNFRSF4 TTLL10 B3GALT6 CPSF3L MIR6727 SCNN1D MIR200A LINC01342 UBE2J2 MIR6726 ACAP3 SDF4 FAM132A
nsv10161	Chr.1:776731 - 1777210 on Build GRCh38	Gain+Loss	CCNL2 NADK CPTP LOC105378948 MXRA8 ISG15 LOC284600 LOC100130417 CDK11A SLC35E2B TAS1R3 FAM87B LOC148413 PUSL1 TNFRSF18 TNFRSF4 MRPL20 MIR6808 TTLL10 TMEM88B DVL1 ATAD3A KLHL17 MIR200A FAM41C UBE2J2 MMP23A PERM1 PLEKHN1 ACAP3 LINC00115 SDF4 FAM132A LOC102724312 LOC100288069 MIR429 MIR200B RNF223 TTLL10-AS1 SLC35E2 AGRN ATAD3C VWA1 NOC2L LOC100288175 C1orf159 AURKAIP1 LINC01128 MIB2 ANKRD65 B3GALT6 CPSF3L MIR6727 MMP23B SCNN1D SSU72 LOC107985728 LINC01342 HES4 TMEM240 LOC107985729 LOC100287934 SAMD11 MIR6726 FNDC10 ATAD3B CDK11B
esv3890636	Chr.1:1304555 - 1353203 on Build GRCh38	Loss	CPSF3L MIR6727 CPTP TAS1R3 MXRA8 PUSL1 ACAP3 MIR6808 DVL1
nsv1000169	Chr.1:1281678 - 1362354 on Build GRCh38	Gain	MIR6726 CPSF3L MIR6727 CPTP SCNN1D TAS1R3 MXRA8 PUSL1 ACAP3 MIR6808 DVL1
nsv950452	Chr.1:1106921 - 1637538 on Build GRCh38	Deletion	MIR429 CCNL2 MIR200B TTLL10-AS1 CPTP MXRA8 ATAD3C VWA1 TAS1R3 C1orf159 LOC148413 PUSL1 TNFRSF18 TNFRSF4 MRPL20 MIR6808 TTLL10 AURKAIP1 TMEM88B MIB2 ANKRD65 DVL1 B3GALT6 CPSF3L MIR6727 MMP23B SCNN1D ATAD3A MIR200A SSU72 LINC01342 TMEM240 LOC107985729 UBE2J2 MIR6726 FNDC10 ACAP3 SDF4 ATAD3B FAM132A LOC102724312 CDK11B
esv2758912	Chr.1:1263940 - 1384492 on Build GRCh38	Loss	CPSF3L MIR6727 CPTP SCNN1D MXRA8 UBE2J2 MIR6726 TAS1R3 PUSL1 ACAP3 MIR6808 AURKAIP1 DVL1
dgv2n67	Chr.1:877618 - 1426500 on Build GRCh38	Gain	MIR429 CCNL2 MIR200B RNF223 TTLL10-AS1 CPTP LOC105378948 MXRA8 AGRN ISG15 LOC284600 LOC100130417 NOC2L TAS1R3 LOC100288175 C1orf159 LOC148413 PUSL1 TNFRSF18 TNFRSF4 MRPL20 MIR6808 TTLL10 AURKAIP1 TMEM88B ANKRD65 DVL1 B3GALT6 CPSF3L MIR6727 SCNN1D KLHL17 MIR200A LOC107985728 LINC01342 HES4 SAMD11 UBE2J2 MIR6726 PERM1 PLEKHN1 ACAP3 SDF4 FAM132A
nsv469848	Chr.1:1146082 - 1322235 on Build GRCh38	Gain	MIR429 B3GALT6 MIR200B CPSF3L MIR6727 TTLL10-AS1 SCNN1D MIR200A UBE2J2 MIR6726 PUSL1 ACAP3 TNFRSF18 TNFRSF4 SDF4 FAM132A TTLL10

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA processing factor

Gene Ontology Categories:

Process(es)

snRNA processing
snRNA transcription from RNA polymerase II promoter

Function(s)

protein binding
hydrolase activity