Hs00594131_cn

• Gene Symbol: CPSF3L
• Assay Reference Genome Location: Chr.1:1313758 on build GRCh38
• Cytoband: 1p36.33

Target Gene Details

• Entrez Gene ID: 54973
• Gene Name: cleavage and polyadenylation specific factor 3-like
• Gene Aliases: CPSF73L, INT11, INTS11, RC-68, RC68
• Location: Chr.1:1311585-1324687 on Build GRCh38
• Assay Gene Location: Within Exon 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CPSF3L	NM_001256456.1	11	1483	NP_001243385.1
	NM_001256460.1	10	1117	NP_001243389.1
	NM_001256462.1	7	716	NP_001243391.1
	NM_001256463.1	7	707	NP_001243392.1
	NM_017871.5	9	1010	NP_060341.2
	XM_011541647.1	11	1161	XP_011539949.1
	XM_011541648.1	11	1165	XP_011539950.1
	XM_011541650.1	9	890	XP_011539952.1
	XM_017001557.1	10	966	XP_016857046.1
	XM_017001558.1	11	1020	XP_016857047.1
	AK000549.1	1	154	BAA91246.1
	AK021939.1	7	673	BAB13943.1
	AK023356.1	9	928	BAB14541.1
	AK056652.1	11	1405
	AK058018.1	7	682
	AK092190.1	6	743
	AK123641.1	1	1413
	AK291387.1	11	1446
	AK297350.1	10	1067
	AL136813.1	9	989	CAB66747.1
	BC000675.2	6	550	AAH00675.2
	BC007978.2	9	972	AAH07978.1
	BC008041.2	6	607	AAH08041.1
	BC013904.2	5	419	AAH13904.2
	BC020199.1	6	607	AAH20199.1
	CR533557.1	9	931	CAG38588.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv482937	Chr.1:10001 - 2368561 on Build GRCh38	Loss	LOC107985729 MIB2 TMEM88B LOC105378949 KLHL17 LINC01128 LOC102724312 CDK11A HES4 LOC100506504 TMEM240 C1orf159 OR4F29 SAMD11 PERM1 MIR1302-2 LOC107984841 WASH7P GNB1 AURKAIP1 MRPL20 MIR6859-1 MXRA8 TNFRSF4 LOC284600 ATAD3A LOC105378948 FNDC10 RNF223 MIR200A DDX11L1 CALML6 MIR6808 MIR6723 LOC100130417 LINC01342 MIR429 CCNL2 MIR200B CPSF3L FAM138A TTLL10 PLEKHN1 SSU72 ATAD3C ATAD3B MMP23B SLC35E2 MTND2P28 UBE2J2 FAM41C SDF4 FAM132A ISG15 LOC729737 SLC35E2B CDK11B TMEM52 LOC100133331 LOC107985728 VWA1 PRKCZ LOC105378592 LOC100288069 B3GALT6 NADK LOC148413 NOC2L CPTP MTND1P23 MIR6726 LOC100132287 OR4F16 LOC100287934 TTLL10-AS1 FAAP20 LOC100288175 DVL1 OR4F5 LOC105378947 LOC105378589 ACAP3 LOC101928626 LOC102725121 TAS1R3 MIR6859-2 CFAP74 MORN1 LOC100134822 AGRN TNFRSF18 MIR6727 SCNN1D LOC100129534 SKI LOC105378591 MMP23A PUSL1 ANKRD65 LINC00115 GABRD FAM87B
nsv544971	Chr.1:1294063 - 1351426 on Build GRCh38	Loss	DVL1 PUSL1 TAS1R3 CPTP MIR6808 MIR6727 ACAP3 CPSF3L MIR6726
nsv544969	Chr.1:1290683 - 1374597 on Build GRCh38	Loss	DVL1 PUSL1 TAS1R3 CPTP MIR6808 AURKAIP1 MXRA8 MIR6727 ACAP3 CPSF3L SCNN1D MIR6726
nsv997291	Chr.1:1306835 - 1376336 on Build GRCh38	Gain	DVL1 PUSL1 TAS1R3 CPTP MIR6808 AURKAIP1 MXRA8 MIR6727 ACAP3 CPSF3L
nsv470680	Chr.1:1070426 - 1378635 on Build GRCh38	Loss	DVL1 RNF223 MIR200A MIR6808 ACAP3 TAS1R3 LINC01342 MIR429 MIR200B CPSF3L TTLL10 B3GALT6 C1orf159 TNFRSF18 CPTP MIR6727 SCNN1D MIR6726 UBE2J2 SDF4 PUSL1 FAM132A AURKAIP1 MXRA8 TNFRSF4 TTLL10-AS1
dgv6n100	Chr.1:1301750 - 1362354 on Build GRCh38	Gain+Loss	DVL1 PUSL1 TAS1R3 CPTP MIR6808 MXRA8 MIR6727 ACAP3 CPSF3L
nsv1160788	Chr.1:1282706 - 1376336 on Build GRCh38	Deletion	DVL1 PUSL1 TAS1R3 CPTP MIR6808 AURKAIP1 MXRA8 MIR6727 ACAP3 CPSF3L SCNN1D MIR6726
nsv1160772	Chr.1:1027585 - 1333467 on Build GRCh38	Duplication	LOC100288175 LOC105378948 RNF223 MIR200A ACAP3 TAS1R3 LINC01342 MIR429 MIR200B AGRN CPSF3L TTLL10 B3GALT6 C1orf159 TNFRSF18 CPTP MIR6727 SCNN1D MIR6726 UBE2J2 SDF4 PUSL1 FAM132A TNFRSF4 TTLL10-AS1
nsv10161	Chr.1:776731 - 1777210 on Build GRCh38	Gain+Loss	LOC107985729 MIB2 SLC35E2B CDK11B TMEM88B LOC107985728 KLHL17 LINC01128 LOC102724312 VWA1 CDK11A HES4 LOC100288069 B3GALT6 TMEM240 NADK LOC148413 C1orf159 NOC2L CPTP SAMD11 PERM1 MIR6726 AURKAIP1 MRPL20 LOC100287934 MXRA8 TNFRSF4 TTLL10-AS1 LOC284600 ATAD3A LOC100288175 LOC105378948 DVL1 FNDC10 RNF223 MIR200A MIR6808 ACAP3 TAS1R3 LOC100130417 LINC01342 MIR429 CCNL2 MIR200B AGRN CPSF3L TTLL10 PLEKHN1 SSU72 ATAD3C TNFRSF18 ATAD3B MMP23B SLC35E2 MIR6727 SCNN1D UBE2J2 FAM41C SDF4 MMP23A PUSL1 ANKRD65 FAM132A LINC00115 ISG15 FAM87B
esv3890636	Chr.1:1304555 - 1353203 on Build GRCh38	Loss	DVL1 PUSL1 TAS1R3 CPTP MIR6808 MXRA8 MIR6727 ACAP3 CPSF3L
nsv1000169	Chr.1:1281678 - 1362354 on Build GRCh38	Gain	DVL1 PUSL1 TAS1R3 CPTP MIR6808 MXRA8 MIR6727 ACAP3 CPSF3L SCNN1D MIR6726
nsv950452	Chr.1:1106921 - 1637538 on Build GRCh38	Deletion	LOC107985729 MIB2 DVL1 FNDC10 CDK11B TMEM88B MIR200A MIR6808 ACAP3 TAS1R3 LOC102724312 VWA1 LINC01342 MIR429 CCNL2 MIR200B CPSF3L TTLL10 B3GALT6 TMEM240 SSU72 ATAD3C LOC148413 C1orf159 TNFRSF18 ATAD3B CPTP MMP23B MIR6727 SCNN1D MIR6726 UBE2J2 SDF4 PUSL1 ANKRD65 FAM132A AURKAIP1 MRPL20 MXRA8 TNFRSF4 TTLL10-AS1 ATAD3A
esv2758912	Chr.1:1263940 - 1384492 on Build GRCh38	Loss	DVL1 CPTP MIR6808 MIR6727 ACAP3 SCNN1D MIR6726 UBE2J2 PUSL1 TAS1R3 AURKAIP1 MXRA8 CPSF3L
dgv2n67	Chr.1:877618 - 1426500 on Build GRCh38	Gain	LOC100288175 LOC105378948 DVL1 RNF223 TMEM88B MIR200A MIR6808 ACAP3 LOC107985728 TAS1R3 KLHL17 LOC100130417 LINC01342 MIR429 CCNL2 MIR200B AGRN CPSF3L HES4 TTLL10 B3GALT6 PLEKHN1 LOC148413 C1orf159 NOC2L TNFRSF18 CPTP MIR6727 SAMD11 PERM1 SCNN1D MIR6726 UBE2J2 SDF4 PUSL1 ANKRD65 FAM132A ISG15 AURKAIP1 MRPL20 MXRA8 TNFRSF4 TTLL10-AS1 LOC284600
nsv469848	Chr.1:1146082 - 1322235 on Build GRCh38	Gain	TTLL10 B3GALT6 MIR200A TNFRSF18 MIR6727 ACAP3 SCNN1D MIR6726 UBE2J2 SDF4 PUSL1 FAM132A MIR429 MIR200B TNFRSF4 TTLL10-AS1 CPSF3L

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA processing factor

Gene Ontology Categories:

Process(es)

snRNA processing
snRNA transcription from RNA polymerase II promoter

Function(s)

protein binding
hydrolase activity