Hs00743656_cn

• Gene Symbol: SOCS6
• Assay Reference Genome Location: Chr.18:70325161 on build GRCh38
• Cytoband: 18q22.2

Target Gene Details

• Entrez Gene ID: 9306
• Gene Name: suppressor of cytokine signaling 6
• Gene Aliases: CIS-4, CIS4, HSPC060, SOCS-4, SOCS-6, SOCS4, SSI4, STAI4, STATI4
• Location: Chr.18:70288901-70330199 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SOCS6	NM_004232.3	2	809	NP_004223.2
	XM_005266783.3	2	771	XP_005266840.1
	XM_017026086.1	2	815	XP_016881575.1
	XM_017026087.1	2	748	XP_016881576.1
	AB006968.1	1	493	BAA22538.1
	AF161545.1	2	669	AAF29032.1
	BC020082.1	2	683	AAH20082.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv32736	Chr.18:69135149 - 71678611 on Build GRCh38	Gain+Loss	DOK6 LINC01541 RTTN CCDC102B CD226 SOCS6 LOC105372179 GTSCR1 LOC101927481 LOC101060542
esv34014	Chr.18:70310065 - 70807720 on Build GRCh38	Loss	SOCS6 GTSCR1 LOC101927481 LOC101060542

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

defense/immunity protein

Gene Ontology Categories:

Process(es)

negative regulation of protein kinase activity
defense response
JAK-STAT cascade
proteasomal protein catabolic process
protein ubiquitination
cytokine-mediated signaling pathway
regulation of growth
negative regulation of JAK-STAT cascade
negative regulation of T cell activation

Function(s)

protein kinase inhibitor activity
protein binding