Hs00873764_cn

• Gene Symbol: CPSF3L
• Assay Reference Genome Location: Chr.1:1321048 on build GRCh38
• Cytoband: 1p36.33

Target Gene Details

• Entrez Gene ID: 54973
• Gene Name: cleavage and polyadenylation specific factor 3-like
• Gene Aliases: CPSF73L, INT11, INTS11, RC-68, RC68
• Location: Chr.1:1311585-1324687 on Build GRCh38
• Assay Gene Location: Overlaps Intron 3 - Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CPSF3L	NM_001256456.1			NP_001243385.1
	NM_001256460.1			NP_001243389.1
	NM_001256462.1			NP_001243391.1
	NM_001256463.1			NP_001243392.1
	NM_017871.5			NP_060341.2
	XM_011541647.1			XP_011539949.1
	XM_011541648.1			XP_011539950.1
	XM_011541650.1			XP_011539952.1
	XM_017001557.1			XP_016857046.1
	XM_017001558.1			XP_016857047.1
	AK021939.1			BAB13943.1
	AK022675.1
	AK023356.1			BAB14541.1
	AK027767.1
	AK056652.1
	AK058018.1
	AK092190.1
	AK291387.1
	AK297350.1
	AL136813.1			CAB66747.1
	BC007978.2			AAH07978.1
	BC008041.2			AAH08041.1
	BC020199.1			AAH20199.1
	CR533557.1			CAG38588.1
	DC295791.1
	DC299237.1
	DC299993.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv482937	Chr.1:10001 - 2368561 on Build GRCh38	Loss	LOC105378592 LOC100133331 CPSF3L LOC100132287 SLC35E2B KLHL17 ATAD3C MIR6726 LOC100287934 DVL1 MIR200A CDK11A UBE2J2 ATAD3A WASH7P FAM41C CCNL2 FAM87B SKI LOC100506504 LOC105378949 SDF4 ATAD3B C1orf159 ISG15 MIR6727 LOC729737 PLEKHN1 MTND2P28 LINC01342 MXRA8 FAAP20 ANKRD65 LOC107985729 LOC284600 PERM1 CPTP CFAP74 SCNN1D LINC00115 MIR6859-1 LOC105378589 LOC105378591 SAMD11 MIR200B B3GALT6 MIB2 OR4F16 GABRD MTND1P23 VWA1 LOC107985728 TTLL10-AS1 MIR6808 LOC100134822 AGRN OR4F5 NADK LOC105378948 FAM132A LOC105378947 LOC102725121 MRPL20 PRKCZ MMP23A SLC35E2 DDX11L1 LOC148413 TNFRSF4 MIR1302-2 TTLL10 HES4 SSU72 NOC2L PUSL1 RNF223 LOC102724312 CDK11B AURKAIP1 LINC01128 TNFRSF18 LOC100129534 LOC100130417 TAS1R3 GNB1 LOC100288069 MMP23B LOC101928626 LOC100288175 LOC107984841 FAM138A MORN1 ACAP3 MIR6723 CALML6 MIR6859-2 FNDC10 TMEM240 MIR429 TMEM88B OR4F29 TMEM52
nsv544971	Chr.1:1294063 - 1351426 on Build GRCh38	Loss	ACAP3 DVL1 TAS1R3 PUSL1 CPSF3L MIR6726 MIR6808 MIR6727 CPTP
nsv544969	Chr.1:1290683 - 1374597 on Build GRCh38	Loss	ACAP3 DVL1 TAS1R3 PUSL1 MXRA8 CPSF3L MIR6726 SCNN1D AURKAIP1 MIR6808 MIR6727 CPTP
nsv997291	Chr.1:1306835 - 1376336 on Build GRCh38	Gain	ACAP3 DVL1 TAS1R3 PUSL1 MXRA8 CPSF3L AURKAIP1 MIR6808 MIR6727 CPTP
nsv470680	Chr.1:1070426 - 1378635 on Build GRCh38	Loss	C1orf159 CPSF3L TNFRSF4 MIR6727 MIR200B B3GALT6 TTLL10 PUSL1 LINC01342 RNF223 MXRA8 TTLL10-AS1 MIR6726 AURKAIP1 MIR6808 TNFRSF18 DVL1 TAS1R3 MIR200A FAM132A UBE2J2 CPTP ACAP3 MIR429 SCNN1D SDF4
dgv6n100	Chr.1:1301750 - 1362354 on Build GRCh38	Gain+Loss	ACAP3 DVL1 TAS1R3 PUSL1 MXRA8 CPSF3L MIR6808 MIR6727 CPTP
esv3584992	Chr.1:1314419 - 1330342 on Build GRCh38	Gain	CPSF3L CPTP
nsv1160788	Chr.1:1282706 - 1376336 on Build GRCh38	Deletion	ACAP3 DVL1 TAS1R3 PUSL1 MXRA8 CPSF3L MIR6726 SCNN1D AURKAIP1 MIR6808 MIR6727 CPTP
nsv1160772	Chr.1:1027585 - 1333467 on Build GRCh38	Duplication	C1orf159 CPSF3L TNFRSF4 MIR6727 MIR200B B3GALT6 TTLL10 PUSL1 LINC01342 RNF223 TTLL10-AS1 MIR6726 AGRN TNFRSF18 LOC105378948 TAS1R3 MIR200A FAM132A LOC100288175 UBE2J2 CPTP ACAP3 MIR429 SCNN1D SDF4
nsv10161	Chr.1:776731 - 1777210 on Build GRCh38	Gain+Loss	CPSF3L SAMD11 MIR200B SLC35E2B B3GALT6 MIB2 KLHL17 ATAD3C VWA1 LOC107985728 TTLL10-AS1 MIR6726 MIR6808 LOC100287934 AGRN NADK DVL1 LOC105378948 MIR200A FAM132A CDK11A UBE2J2 ATAD3A MRPL20 MMP23A FAM41C CCNL2 FAM87B SLC35E2 SDF4 ATAD3B LOC148413 C1orf159 ISG15 TNFRSF4 MIR6727 TTLL10 PLEKHN1 HES4 SSU72 NOC2L PUSL1 LINC01342 RNF223 MXRA8 LOC102724312 CDK11B ANKRD65 AURKAIP1 LOC107985729 LINC01128 TNFRSF18 LOC100130417 TAS1R3 LOC284600 LOC100288069 MMP23B LOC100288175 PERM1 CPTP ACAP3 FNDC10 TMEM240 MIR429 TMEM88B SCNN1D LINC00115
esv3890636	Chr.1:1304555 - 1353203 on Build GRCh38	Loss	ACAP3 DVL1 TAS1R3 PUSL1 MXRA8 CPSF3L MIR6808 MIR6727 CPTP
nsv1000169	Chr.1:1281678 - 1362354 on Build GRCh38	Gain	ACAP3 DVL1 TAS1R3 PUSL1 MXRA8 CPSF3L MIR6726 SCNN1D MIR6808 MIR6727 CPTP
nsv950452	Chr.1:1106921 - 1637538 on Build GRCh38	Deletion	ATAD3B LOC148413 C1orf159 CPSF3L TNFRSF4 MIR6727 MIR200B B3GALT6 TTLL10 MIB2 SSU72 PUSL1 LINC01342 ATAD3C VWA1 MXRA8 LOC102724312 TTLL10-AS1 MIR6726 CDK11B ANKRD65 AURKAIP1 LOC107985729 MIR6808 TNFRSF18 DVL1 TAS1R3 MIR200A FAM132A MMP23B UBE2J2 ATAD3A CPTP ACAP3 MRPL20 FNDC10 TMEM240 MIR429 TMEM88B SCNN1D CCNL2 SDF4
esv2758912	Chr.1:1263940 - 1384492 on Build GRCh38	Loss	DVL1 TAS1R3 CPSF3L MIR6727 UBE2J2 CPTP ACAP3 PUSL1 MXRA8 MIR6726 SCNN1D AURKAIP1 MIR6808
dgv2n67	Chr.1:877618 - 1426500 on Build GRCh38	Gain	LOC148413 C1orf159 ISG15 CPSF3L TNFRSF4 SAMD11 MIR6727 MIR200B B3GALT6 TTLL10 PLEKHN1 HES4 KLHL17 NOC2L PUSL1 LINC01342 RNF223 LOC107985728 MXRA8 TTLL10-AS1 MIR6726 ANKRD65 AURKAIP1 MIR6808 AGRN TNFRSF18 DVL1 LOC105378948 LOC100130417 TAS1R3 MIR200A FAM132A LOC284600 LOC100288175 UBE2J2 PERM1 CPTP ACAP3 MRPL20 MIR429 TMEM88B SCNN1D CCNL2 SDF4
nsv469848	Chr.1:1146082 - 1322235 on Build GRCh38	Gain	TNFRSF18 MIR200A FAM132A CPSF3L TNFRSF4 MIR6727 MIR200B UBE2J2 B3GALT6 ACAP3 TTLL10 PUSL1 TTLL10-AS1 MIR6726 MIR429 SCNN1D SDF4

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA processing factor

Gene Ontology Categories:

Process(es)

snRNA processing
snRNA transcription from RNA polymerase II promoter

Function(s)

protein binding
hydrolase activity