Hs01284788_cn

• Gene Symbol: DHFR2
• Assay Reference Genome Location: Chr.3:94057996 on build GRCh38
• Cytoband: 3q11.2

Target Gene Details

• Entrez Gene ID: 200895
• Gene Name: dihydrofolate reductase 2
• Gene Aliases: DHFRL1, DHFRP4
• Location: Chr.3:94057922-94063656 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DHFR2	NM_001195643.1	2	3966	NP_001182572.1
	NM_176815.4	2	3853	NP_789785.1
	XM_011512537.2	2	4031	XP_011510839.1
	AW104373.1	1	82
	BC045541.1	2	3684	AAH45541.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv590987	Chr.3:93989976 - 94060820 on Build GRCh38	Loss	DHFR2 STX19 ARL13B
esv3893746	Chr.3:93792469 - 94164796 on Build GRCh38	Loss	PROS1 NSUN3 LOC107986037 DHFR2 STX19 ARL13B

More Information

Additional Information:

For this assay, SNP(s) [rs145016958] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

reductase

Gene Ontology Categories:

Process(es)

glycine biosynthetic process
one-carbon metabolic process
nucleotide biosynthetic process
thymidine biosynthetic process
tetrahydrofolate metabolic process
tetrahydrofolate biosynthetic process
oxidation-reduction process

Function(s)

mRNA binding
dihydrofolate reductase activity
NADP binding