Hs01295886_cn

• Gene Symbol: CPSF3L
• Assay Reference Genome Location: Chr.1:1312270 on build GRCh38
• Cytoband: 1p36.33

Target Gene Details

• Entrez Gene ID: 54973
• Gene Name: cleavage and polyadenylation specific factor 3-like
• Gene Aliases: CPSF73L, INT11, INTS11, RC-68, RC68
• Location: Chr.1:1311585-1324687 on Build GRCh38
• Assay Gene Location: Within Exon 17

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CPSF3L	NM_001256456.1	17	2115	NP_001243385.1
	NM_001256460.1	16	1749	NP_001243389.1
	NM_001256462.1	13	1348	NP_001243391.1
	NM_001256463.1	13	1339	NP_001243392.1
	NM_017871.5	15	1642	NP_060341.2
	XM_011541647.1	17	1793	XP_011539949.1
	XM_011541648.1	17	1797	XP_011539950.1
	XM_011541650.1	15	1522	XP_011539952.1
	XM_017001557.1	16	1598	XP_016857046.1
	XM_017001558.1	17	1652	XP_016857047.1
	AK000549.1	7	786	BAA91246.1
	AK021939.1	13	1305	BAB13943.1
	AK023356.1	15	1560	BAB14541.1
	AK056652.1	17	2037
	AK058018.1	13	1314
	AK092190.1	12	1375
	AK123641.1	4	2586
	AK291387.1	17	2078
	AK297350.1	16	1699
	AL136813.1	15	1621	CAB66747.1
	BC000675.2	12	1182	AAH00675.2
	BC007978.2	15	1604	AAH07978.1
	BC008041.2	10	966	AAH08041.1
	BC013904.2	11	1051	AAH13904.2
	BC020199.1	10	966	AAH20199.1
	CR533557.1	15	1563	CAG38588.1
	KF274554.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv482937	Chr.1:10001 - 2368561 on Build GRCh38	Loss	LOC148413 MIR429 LOC107985729 ANKRD65 LOC105378589 LOC100288175 LOC100287934 MIR6726 TNFRSF4 MIR6808 CALML6 TMEM52 NOC2L LOC729737 TNFRSF18 LINC01128 MIR200B CFAP74 ATAD3C FAM41C SDF4 MIR6859-2 LOC100132287 MIB2 LOC100133331 DDX11L1 MMP23B LOC105378947 PERM1 SSU72 FAM132A MIR6723 KLHL17 LOC105378948 LOC105378591 MIR200A RNF223 CDK11B CPSF3L OR4F29 GNB1 LOC100129534 CDK11A MRPL20 SAMD11 TTLL10 LOC100130417 CPTP ACAP3 LOC102725121 MTND2P28 SLC35E2B MIR1302-2 TAS1R3 LOC107985728 MIR6859-1 FNDC10 B3GALT6 TTLL10-AS1 LOC105378949 LOC102724312 ATAD3B LOC100134822 TMEM88B NADK ATAD3A PRKCZ UBE2J2 FAM87B LOC105378592 HES4 CCNL2 VWA1 MXRA8 AGRN SLC35E2 OR4F16 GABRD MMP23A OR4F5 WASH7P TMEM240 AURKAIP1 PUSL1 LINC01342 SKI LOC284600 MTND1P23 PLEKHN1 SCNN1D MORN1 C1orf159 MIR6727 LOC100288069 FAAP20 LINC00115 ISG15 DVL1 LOC101928626 LOC107984841 FAM138A LOC100506504
nsv544971	Chr.1:1294063 - 1351426 on Build GRCh38	Loss	MIR6808 MIR6727 CPTP ACAP3 PUSL1 TAS1R3 CPSF3L MIR6726 DVL1
nsv544969	Chr.1:1290683 - 1374597 on Build GRCh38	Loss	MIR6808 MXRA8 MIR6727 CPTP ACAP3 AURKAIP1 SCNN1D PUSL1 TAS1R3 CPSF3L MIR6726 DVL1
nsv997291	Chr.1:1306835 - 1376336 on Build GRCh38	Gain	MIR6808 MXRA8 MIR6727 CPTP ACAP3 AURKAIP1 PUSL1 TAS1R3 CPSF3L DVL1
nsv470680	Chr.1:1070426 - 1378635 on Build GRCh38	Loss	MIR429 FAM132A AURKAIP1 PUSL1 LINC01342 TAS1R3 B3GALT6 TTLL10-AS1 MIR200A RNF223 SCNN1D CPSF3L MIR6726 TNFRSF4 C1orf159 MIR6808 UBE2J2 MIR6727 TNFRSF18 TTLL10 DVL1 MIR200B MXRA8 CPTP ACAP3 SDF4
dgv6n100	Chr.1:1301750 - 1362354 on Build GRCh38	Gain+Loss	MIR6808 MXRA8 MIR6727 CPTP ACAP3 PUSL1 TAS1R3 CPSF3L DVL1
nsv1160788	Chr.1:1282706 - 1376336 on Build GRCh38	Deletion	MIR6808 MXRA8 MIR6727 CPTP ACAP3 AURKAIP1 SCNN1D PUSL1 TAS1R3 CPSF3L MIR6726 DVL1
nsv1160772	Chr.1:1027585 - 1333467 on Build GRCh38	Duplication	MIR429 FAM132A PUSL1 LINC01342 TAS1R3 B3GALT6 TTLL10-AS1 LOC100288175 LOC105378948 MIR200A RNF223 SCNN1D CPSF3L MIR6726 TNFRSF4 C1orf159 UBE2J2 MIR6727 TNFRSF18 TTLL10 MIR200B AGRN CPTP ACAP3 SDF4
nsv10161	Chr.1:776731 - 1777210 on Build GRCh38	Gain+Loss	LOC148413 SLC35E2B MIR429 LOC107985729 TAS1R3 LOC107985728 FNDC10 B3GALT6 ANKRD65 TTLL10-AS1 LOC100288175 LOC102724312 ATAD3B TMEM88B NADK ATAD3A LOC100287934 MIR6726 TNFRSF4 MIR6808 UBE2J2 FAM87B HES4 NOC2L CCNL2 TNFRSF18 LINC01128 MIR200B VWA1 MXRA8 AGRN ATAD3C SLC35E2 FAM41C MMP23A SDF4 MIB2 MMP23B PERM1 SSU72 FAM132A TMEM240 KLHL17 AURKAIP1 PUSL1 LINC01342 LOC284600 LOC105378948 PLEKHN1 MIR200A RNF223 SCNN1D CDK11B CPSF3L C1orf159 CDK11A MIR6727 LOC100288069 MRPL20 SAMD11 LINC00115 TTLL10 ISG15 DVL1 LOC100130417 CPTP ACAP3
esv3890636	Chr.1:1304555 - 1353203 on Build GRCh38	Loss	MIR6808 MXRA8 MIR6727 CPTP ACAP3 PUSL1 TAS1R3 CPSF3L DVL1
nsv1000169	Chr.1:1281678 - 1362354 on Build GRCh38	Gain	MIR6808 MXRA8 MIR6727 CPTP ACAP3 SCNN1D PUSL1 TAS1R3 CPSF3L MIR6726 DVL1
nsv950452	Chr.1:1106921 - 1637538 on Build GRCh38	Deletion	LOC148413 MIR429 SSU72 LOC107985729 FAM132A TMEM240 AURKAIP1 PUSL1 LINC01342 TAS1R3 FNDC10 B3GALT6 ANKRD65 TTLL10-AS1 LOC102724312 ATAD3B MIR200A TMEM88B SCNN1D CDK11B ATAD3A CPSF3L MIR6726 TNFRSF4 C1orf159 MIR6808 UBE2J2 MIR6727 CCNL2 MRPL20 TNFRSF18 TTLL10 DVL1 MIR200B VWA1 MXRA8 ATAD3C CPTP ACAP3 SDF4 MIB2 MMP23B
esv2758912	Chr.1:1263940 - 1384492 on Build GRCh38	Loss	MIR6808 UBE2J2 MIR6727 AURKAIP1 PUSL1 TAS1R3 DVL1 MXRA8 CPTP ACAP3 SCNN1D CPSF3L MIR6726
dgv2n67	Chr.1:877618 - 1426500 on Build GRCh38	Gain	PERM1 LOC148413 MIR429 FAM132A KLHL17 AURKAIP1 PUSL1 LINC01342 TAS1R3 LOC107985728 B3GALT6 ANKRD65 TTLL10-AS1 LOC100288175 LOC284600 LOC105378948 PLEKHN1 MIR200A RNF223 TMEM88B SCNN1D CPSF3L MIR6726 TNFRSF4 C1orf159 MIR6808 UBE2J2 MIR6727 HES4 NOC2L CCNL2 MRPL20 TNFRSF18 SAMD11 TTLL10 ISG15 DVL1 MIR200B MXRA8 AGRN LOC100130417 CPTP ACAP3 SDF4
nsv469848	Chr.1:1146082 - 1322235 on Build GRCh38	Gain	MIR429 UBE2J2 MIR6727 FAM132A PUSL1 TNFRSF18 TTLL10 B3GALT6 TTLL10-AS1 MIR200B MIR200A ACAP3 SCNN1D CPSF3L SDF4 MIR6726 TNFRSF4

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA processing factor

Gene Ontology Categories:

Process(es)

snRNA processing
snRNA transcription from RNA polymerase II promoter

Function(s)

protein binding
hydrolase activity