Hs01320160_cn

• Gene Symbol: CLP1
• Assay Reference Genome Location: Chr.11:57660062 on build GRCh38
• Cytoband: 11q12.1

Target Gene Details

• Entrez Gene ID: 10978
• Gene Name: cleavage and polyadenylation factor I subunit 1
• Gene Aliases: HEAB, hClp1
• Location: Chr.11:57657744-57661865 on Build GRCh38
• Assay Gene Location: Overlaps Exon 2 - Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CLP1	NM_001142597.1			NP_001136069.1
	NM_006831.2			NP_006822.1
	AK300232.1
	AK313007.1
	BC000446.1			AAH00446.1
	U73524.1			AAC50780.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832163	Chr.11:57531881 - 57713578 on Build GRCh38	Gain	ZDHHC5 SMTNL1 YPEL4 UBE2L6 SERPING1 TMX2 MED19 MIR130A TMX2-CTNND1 CLP1
nsv508633	Chr.11:57652112 - 57792573 on Build GRCh38	Deletion	ZDHHC5 TMX2 C11orf31 MED19 CTNND1 TMX2-CTNND1 BTBD18 CLP1
nsv832164	Chr.11:57640144 - 57811353 on Build GRCh38	Loss	ZDHHC5 YPEL4 TMX2 C11orf31 MED19 MIR130A CTNND1 TMX2-CTNND1 BTBD18 CLP1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

mRNA polyadenylation factor

Gene Ontology Categories:

Process(es)

mRNA splicing, via spliceosome
termination of RNA polymerase II transcription
mRNA polyadenylation
mRNA cleavage
tRNA splicing, via endonucleolytic cleavage and ligation
phosphorylation
cerebellar cortex development
targeting of mRNA for destruction involved in RNA interference
mRNA 3'-end processing
siRNA loading onto RISC involved in RNA interference

Function(s)

ATP binding
ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity
polydeoxyribonucleotide kinase activity
ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity