Hs01446199_cn

• Gene Symbol: DHFR2
• Assay Reference Genome Location: Chr.3:94060178 on build GRCh38
• Cytoband: 3q11.2

Target Gene Details

• Entrez Gene ID: 200895
• Gene Name: dihydrofolate reductase 2
• Gene Aliases: DHFRL1, DHFRP4
• Location: Chr.3:94057922-94063656 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DHFR2	NM_001195643.1	2	1784	NP_001182572.1
	NM_176815.4	2	1671	NP_789785.1
	XM_011512537.2	2	1849	XP_011510839.1
	AK122674.1	2	1784
	AL832912.1	2	1460	CAH10617.1
	BC045541.1	2	1502	AAH45541.1
	BC063379.1	2	1460	AAH63379.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv590987	Chr.3:93989976 - 94060820 on Build GRCh38	Loss	DHFR2 STX19 ARL13B
esv3893746	Chr.3:93792469 - 94164796 on Build GRCh38	Loss	DHFR2 NSUN3 STX19 ARL13B PROS1 LOC107986037

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

reductase

Gene Ontology Categories:

Process(es)

glycine biosynthetic process
one-carbon metabolic process
nucleotide biosynthetic process
thymidine biosynthetic process
tetrahydrofolate metabolic process
tetrahydrofolate biosynthetic process
oxidation-reduction process

Function(s)

mRNA binding
dihydrofolate reductase activity
NADP binding