Hs01467476_cn

• Gene Symbol: PPP1R16A
• Assay Reference Genome Location: Chr.8:144497458 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 84988
• Gene Name: protein phosphatase 1 regulatory subunit 16A
• Gene Aliases: MYPT3
• Location: Chr.8:144477987-144502121 on Build GRCh38
• Assay Gene Location: Overlaps Exon 5 - Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPP1R16A	XM_005272350.2			XP_005272407.1
	XM_011517349.2			XP_011515651.1
	XM_017013912.1			XP_016869401.1
	XM_017013913.1			XP_016869402.1
	XM_017013914.1			XP_016869403.1
	XM_017013915.1			XP_016869404.1
	AK090471.1	4	1132	BAC03452.1
	BC007854.2			AAH07854.1
	BC049841.1			AAH49841.1
	BC053506.1			AAH53506.1
	BT006845.1			AAP35491.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	PARP10 SPATC1 ADCK5 KIFC2 HSF1 SCX MIR661 MIR6847 MIR1234 CPSF1 GPT CYC1 MIR6848 LOC101928902 SHARPIN FOXH1 DGAT1 LRRC14 SCRT1 GPAA1 OPLAH MROH1 BOP1 PPP1R16A MAF1 SLC39A4 TONSL-AS1 LOC101928953 MIR6893 VPS28 PLEC EXOSC4 GRINA HGH1 CYHR1 RECQL4 SLC52A2 SMPD5 MIR6849 TONSL MFSD3 TMEM249 FBXL6 MIR939 MIR6846 MIR7112 WDR97
nsv612951	Chr.8:144479830 - 144677692 on Build GRCh38	Loss	LRRC14 RECQL4 LOC101928953 LRRC24 C8orf82 MFSD3 PPP1R16A GPT ARHGAP39
nsv831489	Chr.8:144342140 - 144544026 on Build GRCh38	Loss	ADCK5 KIFC2 MIR1234 CPSF1 GPT LOC101928902 FOXH1 LRRC14 LRRC24 PPP1R16A SLC39A4 TONSL-AS1 LOC101928953 C8orf82 MIR6893 VPS28 ARHGAP39 CYHR1 RECQL4 SLC52A2 MIR6849 TONSL MFSD3 TMEM249 FBXL6 MIR939
dgv12439n54	Chr.8:144438306 - 144525122 on Build GRCh38	Loss	FOXH1 CYHR1 TONSL-AS1 LRRC14 KIFC2 RECQL4 LOC101928953 LRRC24 TONSL MFSD3 PPP1R16A GPT
nsv612955	Chr.8:144494912 - 144502322 on Build GRCh38	Loss	LOC101928953 PPP1R16A GPT
nsv482126	Chr.8:144496726 - 144502120 on Build GRCh38	Gain	LOC101928953 PPP1R16A
dgv907n27	Chr.8:144416180 - 144525122 on Build GRCh38	Loss	TONSL-AS1 KIFC2 LOC101928953 MIR6893 VPS28 GPT FOXH1 CYHR1 LRRC14 RECQL4 LRRC24 TONSL MFSD3 PPP1R16A SLC39A4
dgv12442n54	Chr.8:144492696 - 144516381 on Build GRCh38	Loss	RECQL4 LOC101928953 MFSD3 PPP1R16A GPT
dgv12434n54	Chr.8:144270080 - 144516801 on Build GRCh38	Loss	ADCK5 KIFC2 HSF1 MIR1234 CPSF1 GPT MIR6848 LOC101928902 FOXH1 DGAT1 SCRT1 BOP1 PPP1R16A SLC39A4 TONSL-AS1 LOC101928953 MIR6893 VPS28 CYHR1 RECQL4 SLC52A2 MIR6849 TONSL MFSD3 TMEM249 FBXL6 MIR939
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	PARP10 SPATC1 ADCK5 KIFC2 HSF1 SCX MIR661 MIR6847 MIR1234 CPSF1 GPT CYC1 MIR6848 LOC101928902 SHARPIN FOXH1 DGAT1 LRRC14 SCRT1 GPAA1 OPLAH MROH1 BOP1 PPP1R16A MAF1 SLC39A4 TONSL-AS1 LOC101928953 MIR6893 VPS28 PLEC EXOSC4 GRINA HGH1 CYHR1 RECQL4 SLC52A2 SMPD5 MIR6849 TONSL MFSD3 TMEM249 FBXL6 MIR939 MIR6846 MIR7112 WDR97
nsv612940	Chr.8:144436292 - 144613673 on Build GRCh38	Loss	TONSL-AS1 KIFC2 LOC101928953 C8orf82 GPT ARHGAP39 FOXH1 CYHR1 LRRC14 RECQL4 LRRC24 TONSL MFSD3 PPP1R16A
nsv428208	Chr.8:144041826 - 144722291 on Build GRCh38	Gain	SPATC1 ADCK5 KIFC2 HSF1 SCX MIR6847 MIR1234 CPSF1 GPT CYC1 MIR6848 LOC101928902 SHARPIN FOXH1 DGAT1 LRRC14 LRRC24 SCRT1 GPAA1 OPLAH MROH1 BOP1 PPP1R16A MAF1 SLC39A4 TONSL-AS1 LOC101928953 C8orf82 MIR6893 VPS28 EXOSC4 ZNF251 ARHGAP39 HGH1 CYHR1 RECQL4 SLC52A2 SMPD5 MIR6849 TONSL MFSD3 TMEM249 FBXL6 MIR939 MIR6846 MIR7112 WDR97
esv29999	Chr.8:144456732 - 144525122 on Build GRCh38	Loss	FOXH1 CYHR1 LRRC14 KIFC2 RECQL4 LOC101928953 LRRC24 MFSD3 PPP1R16A GPT

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphatase modulator

Gene Ontology Categories:

Process(es)

regulation of catalytic activity

Function(s)

protein binding
protein phosphatase type 1 regulator activity