Hs01625224_cn

• Gene Symbol: CPSF3L
• Assay Reference Genome Location: Chr.1:1312669 on build GRCh38
• Cytoband: 1p36.33

Target Gene Details

• Entrez Gene ID: 54973
• Gene Name: cleavage and polyadenylation specific factor 3-like
• Gene Aliases: CPSF73L, INT11, INTS11, RC-68, RC68
• Location: Chr.1:1311585-1324687 on Build GRCh38
• Assay Gene Location: Overlaps Intron 15 - Exon 15

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CPSF3L	NM_001256456.1			NP_001243385.1
	NM_001256460.1			NP_001243389.1
	NM_001256462.1			NP_001243391.1
	NM_001256463.1			NP_001243392.1
	NM_017871.5			NP_060341.2
	XM_011541647.1			XP_011539949.1
	XM_011541648.1			XP_011539950.1
	XM_011541650.1			XP_011539952.1
	XM_017001557.1			XP_016857046.1
	XM_017001558.1			XP_016857047.1
	AK000549.1			BAA91246.1
	AK021939.1			BAB13943.1
	AK023356.1			BAB14541.1
	AK056652.1
	AK058018.1
	AK092190.1
	AK123641.1
	AK291387.1
	AK297350.1
	AL136813.1			CAB66747.1
	BC000675.2			AAH00675.2
	BC007978.2			AAH07978.1
	BC008041.2			AAH08041.1
	BC013904.2			AAH13904.2
	BC020199.1			AAH20199.1
	CR533557.1			CAG38588.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv482937	Chr.1:10001 - 2368561 on Build GRCh38	Loss	LOC105378591 MIR6726 PRKCZ C1orf159 LOC102724312 MIR1302-2 MIR429 SLC35E2 CCNL2 LOC100130417 MTND1P23 LOC107985728 TMEM88B CDK11A SSU72 ISG15 LOC100288069 MRPL20 UBE2J2 TAS1R3 FAAP20 MMP23B TMEM240 SCNN1D NOC2L OR4F29 LOC100133331 SAMD11 LOC284600 PUSL1 LOC105378947 MMP23A LOC101928626 LOC100129534 FAM138A SLC35E2B LOC100288175 OR4F5 MIR6808 GNB1 ACAP3 CDK11B MIR6859-2 NADK MIR200B B3GALT6 MIR6723 WASH7P FAM87B TMEM52 LOC100287934 FAM41C LOC107984841 LOC105378589 AURKAIP1 LOC100134822 RNF223 PERM1 LINC01128 ANKRD65 LOC729737 ATAD3A CPSF3L CALML6 TNFRSF18 MIR6727 DVL1 GABRD LOC100506504 LOC102725121 FNDC10 CPTP CFAP74 ATAD3C TTLL10-AS1 FAM132A SKI HES4 TNFRSF4 KLHL17 PLEKHN1 LOC107985729 LOC105378948 MIR6859-1 LINC00115 LINC01342 LOC148413 MORN1 LOC105378949 MIR200A DDX11L1 OR4F16 ATAD3B AGRN TTLL10 MXRA8 LOC105378592 LOC100132287 SDF4 MIB2 VWA1 MTND2P28
nsv544971	Chr.1:1294063 - 1351426 on Build GRCh38	Loss	MIR6808 MIR6726 MIR6727 DVL1 PUSL1 ACAP3 TAS1R3 CPTP CPSF3L
nsv544969	Chr.1:1290683 - 1374597 on Build GRCh38	Loss	MIR6808 MXRA8 MIR6726 AURKAIP1 MIR6727 SCNN1D DVL1 PUSL1 ACAP3 TAS1R3 CPTP CPSF3L
nsv997291	Chr.1:1306835 - 1376336 on Build GRCh38	Gain	MIR6808 MXRA8 AURKAIP1 MIR6727 DVL1 PUSL1 ACAP3 TAS1R3 CPTP CPSF3L
nsv470680	Chr.1:1070426 - 1378635 on Build GRCh38	Loss	MIR200B B3GALT6 MIR6726 TTLL10-AS1 FAM132A C1orf159 TNFRSF4 AURKAIP1 SCNN1D LINC01342 MIR429 PUSL1 RNF223 MIR200A CPSF3L MIR6808 TTLL10 MXRA8 TNFRSF18 SDF4 MIR6727 DVL1 ACAP3 UBE2J2 TAS1R3 CPTP
dgv6n100	Chr.1:1301750 - 1362354 on Build GRCh38	Gain+Loss	MIR6808 MXRA8 MIR6727 DVL1 PUSL1 ACAP3 TAS1R3 CPTP CPSF3L
nsv1160788	Chr.1:1282706 - 1376336 on Build GRCh38	Deletion	MIR6808 MXRA8 MIR6726 AURKAIP1 MIR6727 SCNN1D DVL1 PUSL1 ACAP3 TAS1R3 CPTP CPSF3L
nsv1160772	Chr.1:1027585 - 1333467 on Build GRCh38	Duplication	MIR200B B3GALT6 MIR6726 TTLL10-AS1 FAM132A C1orf159 TNFRSF4 LOC105378948 SCNN1D LINC01342 MIR429 PUSL1 RNF223 MIR200A CPSF3L LOC100288175 AGRN TTLL10 TNFRSF18 SDF4 MIR6727 ACAP3 UBE2J2 TAS1R3 CPTP
nsv10161	Chr.1:776731 - 1777210 on Build GRCh38	Gain+Loss	NADK MIR200B B3GALT6 MIR6726 FAM87B C1orf159 LOC100287934 FAM41C LOC102724312 AURKAIP1 MIR429 SLC35E2 CCNL2 RNF223 LOC100130417 PERM1 LINC01128 ANKRD65 ATAD3A LOC107985728 TMEM88B CDK11A CPSF3L TNFRSF18 SSU72 ISG15 MIR6727 DVL1 LOC100288069 FNDC10 MRPL20 UBE2J2 TAS1R3 CPTP ATAD3C TTLL10-AS1 FAM132A HES4 TNFRSF4 KLHL17 MMP23B PLEKHN1 TMEM240 LOC107985729 LOC105378948 SCNN1D NOC2L LINC00115 SAMD11 LINC01342 LOC148413 LOC284600 PUSL1 MMP23A MIR200A SLC35E2B LOC100288175 ATAD3B AGRN MIR6808 TTLL10 MXRA8 SDF4 MIB2 VWA1 ACAP3 CDK11B
esv3890636	Chr.1:1304555 - 1353203 on Build GRCh38	Loss	MIR6808 MXRA8 MIR6727 DVL1 PUSL1 ACAP3 TAS1R3 CPTP CPSF3L
nsv1000169	Chr.1:1281678 - 1362354 on Build GRCh38	Gain	MIR6808 MXRA8 MIR6726 MIR6727 SCNN1D DVL1 PUSL1 ACAP3 TAS1R3 CPTP CPSF3L
nsv950452	Chr.1:1106921 - 1637538 on Build GRCh38	Deletion	MIR200B ATAD3C B3GALT6 MIR6726 TTLL10-AS1 FAM132A C1orf159 TNFRSF4 MMP23B TMEM240 LOC107985729 LOC102724312 AURKAIP1 SCNN1D LINC01342 LOC148413 MIR429 PUSL1 CCNL2 MIR200A ANKRD65 ATAD3A TMEM88B CPSF3L ATAD3B MIR6808 TTLL10 MXRA8 TNFRSF18 SDF4 SSU72 MIR6727 MIB2 VWA1 DVL1 FNDC10 ACAP3 MRPL20 UBE2J2 TAS1R3 CDK11B CPTP
esv2758912	Chr.1:1263940 - 1384492 on Build GRCh38	Loss	MIR6726 CPSF3L MIR6808 MXRA8 AURKAIP1 MIR6727 SCNN1D DVL1 PUSL1 ACAP3 UBE2J2 TAS1R3 CPTP
dgv2n67	Chr.1:877618 - 1426500 on Build GRCh38	Gain	MIR200B B3GALT6 MIR6726 TTLL10-AS1 FAM132A C1orf159 HES4 TNFRSF4 KLHL17 PLEKHN1 LOC105378948 AURKAIP1 SCNN1D NOC2L SAMD11 LINC01342 LOC148413 LOC284600 MIR429 PUSL1 CCNL2 RNF223 LOC100130417 PERM1 MIR200A ANKRD65 LOC107985728 TMEM88B CPSF3L LOC100288175 AGRN MIR6808 TTLL10 MXRA8 TNFRSF18 SDF4 ISG15 MIR6727 DVL1 ACAP3 MRPL20 UBE2J2 TAS1R3 CPTP
nsv469848	Chr.1:1146082 - 1322235 on Build GRCh38	Gain	MIR200B B3GALT6 MIR6726 TTLL10-AS1 FAM132A MIR200A TNFRSF4 CPSF3L TTLL10 TNFRSF18 SDF4 MIR6727 SCNN1D MIR429 PUSL1 ACAP3 UBE2J2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA processing factor

Gene Ontology Categories:

Process(es)

snRNA processing
snRNA transcription from RNA polymerase II promoter

Function(s)

protein binding
hydrolase activity