Hs01844642_cn

• Gene Symbol: BCO2
• Assay Reference Genome Location: Chr.11:112216270 on build GRCh38
• Cytoband: 11q23.1

Target Gene Details

• Entrez Gene ID: 83875
• Gene Name: beta-carotene oxygenase 2
• Gene Aliases: B-DIOX-II, BCDO2
• Location: Chr.11:112175485-112218929 on Build GRCh38
• Assay Gene Location: Overlaps Intron 11 - Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BCO2	NM_001037290.2			NP_001032367.2
	NM_001256397.1			NP_001243326.1
	NM_001256398.1			NP_001243327.1
	NM_001256400.1			NP_001243329.1
	NM_031938.5			NP_114144.4
	AB096252.1
	AF276432.1			AAK69433.1
	AJ290393.1			CAC27994.1
	AK027801.1			BAB55379.1
	AK297853.1
	AK315300.1
	BC041656.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv493	Chr.11:112214950 - 112216686 on Build GRCh38	Insertion	BCO2
esv3579908	Chr.11:112173319 - 112217076 on Build GRCh38	Loss	BCO2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

retinoid metabolic process
carotenoid metabolic process
carotene metabolic process
carotene catabolic process
xanthophyll metabolic process
retinoic acid metabolic process
retinal metabolic process
regulation of mitochondrial membrane potential
oxidation-reduction process
regulation of reactive oxygen species metabolic process

Function(s)

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
metal ion binding