Hs02408917_cn

• Gene Symbol: HES2
• Assay Reference Genome Location: Chr.1:6416487 on build GRCh38
• Cytoband: 1p36.31

Target Gene Details

• Entrez Gene ID: 54626
• Gene Name: hes family bHLH transcription factor 2
• Gene Aliases: bHLHb40
• Location: Chr.1:6415232-6419919 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HES2	NM_019089.4	4	3007	NP_061962.2
	AK023754.1	1	2192
	AK091122.1	4	3007
	BC012091.1			AAH12091.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1009548	Chr.1:6342976 - 6517352 on Build GRCh38	Loss	ACOT7 PLEKHG5 HES2 MIR4252 TNFRSF25 ESPN
dgv2n27	Chr.1:6396412 - 6512115 on Build GRCh38	Loss	PLEKHG5 HES2 MIR4252 TNFRSF25 ESPN
nsv954048	Chr.1:6414241 - 6500740 on Build GRCh38	Deletion	PLEKHG5 HES2 MIR4252 TNFRSF25 ESPN
nsv545240	Chr.1:6351154 - 6512115 on Build GRCh38	Loss	ACOT7 PLEKHG5 HES2 MIR4252 TNFRSF25 ESPN
nsv508836	Chr.1:6406896 - 6501029 on Build GRCh38	Insertion	PLEKHG5 HES2 MIR4252 TNFRSF25 ESPN

More Information

Additional Information:

For this assay, SNP(s) [rs78326109] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
negative regulation of transcription, DNA-templated

Function(s)

double-stranded DNA binding
transcription factor binding
protein dimerization activity