Hs02631563_cn

• Gene Symbol: MS4A2
• Assay Reference Genome Location: Chr.11:60097373 on build GRCh38
• Cytoband: 11q12.1

Target Gene Details

• Entrez Gene ID: 2206
• Gene Name: membrane spanning 4-domains A2
• Gene Aliases: APY, ATOPY, FCER1B, FCERI, IGEL, IGER, IGHER, MS4A1
• Location: Chr.11:60088261-60098467 on Build GRCh38
• Assay Gene Location: Within Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MS4A2	NM_000139.4	7	2554	NP_000130.1
	NM_001256916.1	6	2419	NP_001243845.1
	XM_005273846.4	8	2869	XP_005273903.1
	XM_011544850.2	8	2487	XP_011543152.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv468579	Chr.11:60046814 - 60207927 on Build GRCh38	Gain	MS4A3 MS4A2 OOSP2 MS4A6A MS4A4E
dgv201e214	Chr.11:60084926 - 60104676 on Build GRCh38	Loss	MS4A2
esv3626549	Chr.11:60093431 - 60115836 on Build GRCh38	Loss	MS4A2
nsv832173	Chr.11:60021411 - 60173087 on Build GRCh38	Gain	MS4A3 MS4A2 LOC107987155 OOSP2 MS4A6A

More Information

Additional Information:

For this assay, SNP(s) [rs139319787] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transporter

Gene Ontology Categories:

Process(es)

inflammatory response
immune response
Fc-epsilon receptor signaling pathway

Function(s)

IgE binding