Hs02679311_cn

• Gene Symbol: CLP1
• Assay Reference Genome Location: Chr.11:57657814 on build GRCh38
• Cytoband: 11q12.1

Target Gene Details

• Entrez Gene ID: 10978
• Gene Name: cleavage and polyadenylation factor I subunit 1
• Gene Aliases: HEAB, hClp1
• Location: Chr.11:57657744-57661865 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CLP1	NM_001142597.1	1	71	NP_001136069.1
	NM_006831.2	1	71	NP_006822.1
	AK300232.1	1	54
	AK313007.1	1	56
	BC000446.1	1	59	AAH00446.1
	DA922553.1	1	71
	U73524.1	1	657	AAC50780.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832163	Chr.11:57531881 - 57713578 on Build GRCh38	Gain	UBE2L6 MIR130A TMX2-CTNND1 CLP1 ZDHHC5 TMX2 MED19 SERPING1 SMTNL1 YPEL4
nsv508633	Chr.11:57652112 - 57792573 on Build GRCh38	Deletion	BTBD18 CTNND1 TMX2-CTNND1 CLP1 ZDHHC5 TMX2 C11orf31 MED19
nsv832164	Chr.11:57640144 - 57811353 on Build GRCh38	Loss	MIR130A BTBD18 CTNND1 TMX2-CTNND1 CLP1 ZDHHC5 TMX2 C11orf31 MED19 YPEL4

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

mRNA polyadenylation factor

Gene Ontology Categories:

Process(es)

mRNA splicing, via spliceosome
termination of RNA polymerase II transcription
mRNA polyadenylation
mRNA cleavage
tRNA splicing, via endonucleolytic cleavage and ligation
phosphorylation
cerebellar cortex development
targeting of mRNA for destruction involved in RNA interference
mRNA 3'-end processing
siRNA loading onto RISC involved in RNA interference

Function(s)

ATP binding
ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity
polydeoxyribonucleotide kinase activity
ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity