Hs02718829_cn

• Gene Symbol: GCN1
• Assay Reference Genome Location: Chr.12:120127822 on build GRCh38
• Cytoband: 12q24.23

Target Gene Details

• Entrez Gene ID: 10985
• Gene Name: GCN1, eIF2 alpha kinase activator homolog
• Gene Aliases: GCN1L, GCN1L1, PRIC295
• Location: Chr.12:120127210-120194710 on Build GRCh38
• Assay Gene Location: Within Exon 58

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GCN1	NM_006836.1	58	8056	NP_006827.1
	BC021129.1	7	928	AAH21129.1
	BC032335.1	7	883	AAH32335.1
	BC046177.1	4	599	AAH46177.1
	BC064346.1	6	772	AAH64346.1
	BC153881.1	58	8056
	D86973.2	58	8056
	U77700.1	36	5521	AAC51648.1
	U88836.1	19	3014	AAD00655.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv519657	Chr.12:120095892 - 120238287 on Build GRCh38	Loss	GCN1 PXN-AS1 RPLP0 RAB35 PXN MIR4498

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

translation
regulation of translation
positive regulation of kinase activity
cellular response to amino acid starvation
positive regulation of transcription from RNA polymerase II promoter in response to stress
regulation of protein kinase activity
cell-cell adhesion
cellular response to leucine starvation

Function(s)

translation factor activity, RNA binding
protein kinase regulator activity
protein kinase binding
ribosome binding
poly(A) RNA binding
cadherin binding involved in cell-cell adhesion