Hs02883229_cn

• Gene Symbol: CPSF3L
• Assay Reference Genome Location: Chr.1:1315514 on build GRCh38
• Cytoband: 1p36.33

Target Gene Details

• Entrez Gene ID: 54973
• Gene Name: cleavage and polyadenylation specific factor 3-like
• Gene Aliases: CPSF73L, INT11, INTS11, RC-68, RC68
• Location: Chr.1:1311585-1324687 on Build GRCh38
• Assay Gene Location: Overlaps Intron 7 - Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CPSF3L	NM_001256456.1			NP_001243385.1
	NM_001256460.1			NP_001243389.1
	NM_001256462.1			NP_001243391.1
	NM_001256463.1			NP_001243392.1
	NM_017871.5			NP_060341.2
	XM_011541647.1			XP_011539949.1
	XM_011541648.1			XP_011539950.1
	XM_011541650.1			XP_011539952.1
	XM_017001557.1			XP_016857046.1
	XM_017001558.1			XP_016857047.1
	AK021939.1			BAB13943.1
	AK023356.1			BAB14541.1
	AK056652.1
	AK058018.1
	AK092190.1
	AK291387.1
	AK297350.1
	AL136813.1			CAB66747.1
	BC000675.2			AAH00675.2
	BC007978.2			AAH07978.1
	BC008041.2			AAH08041.1
	BC013904.2			AAH13904.2
	BC020199.1			AAH20199.1
	CR533557.1			CAG38588.1
	DC299237.1
	DC299993.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv482937	Chr.1:10001 - 2368561 on Build GRCh38	Loss	AURKAIP1 MXRA8 GNB1 FAAP20 TMEM240 ATAD3A TNFRSF4 SCNN1D KLHL17 LOC105378947 OR4F5 MIR6723 LOC100134822 TNFRSF18 FNDC10 LOC100132287 PLEKHN1 LOC100506504 ATAD3C FAM41C RNF223 C1orf159 LOC100288175 TMEM88B MTND2P28 SKI LOC107985728 DDX11L1 SLC35E2 MIR429 PUSL1 VWA1 PRKCZ MIR6808 CPSF3L AGRN SSU72 LOC105378949 CFAP74 LOC284600 HES4 LOC100130417 FAM132A UBE2J2 LOC105378591 CDK11B ISG15 MORN1 OR4F16 LOC107984841 B3GALT6 MIR6726 TTLL10-AS1 SAMD11 LOC100129534 MMP23B DVL1 LOC148413 NADK MIB2 SLC35E2B LOC105378592 NOC2L LOC101928626 MMP23A LINC01128 LOC107985729 LOC102725121 MIR200A MIR6727 LOC729737 LOC105378589 MRPL20 MIR1302-2 FAM138A LINC00115 TTLL10 CDK11A CCNL2 SDF4 ACAP3 MTND1P23 FAM87B LOC100287934 CPTP CALML6 MIR200B ANKRD65 LOC105378948 LOC100133331 PERM1 LOC100288069 MIR6859-2 ATAD3B TAS1R3 TMEM52 LINC01342 MIR6859-1 WASH7P GABRD LOC102724312 OR4F29
nsv544971	Chr.1:1294063 - 1351426 on Build GRCh38	Loss	MIR6808 ACAP3 DVL1 CPSF3L MIR6727 MIR6726 CPTP TAS1R3 PUSL1
nsv544969	Chr.1:1290683 - 1374597 on Build GRCh38	Loss	MIR6808 AURKAIP1 SCNN1D ACAP3 DVL1 MXRA8 CPSF3L MIR6727 MIR6726 CPTP TAS1R3 PUSL1
nsv997291	Chr.1:1306835 - 1376336 on Build GRCh38	Gain	MIR6808 AURKAIP1 ACAP3 DVL1 MXRA8 CPSF3L MIR6727 CPTP TAS1R3 PUSL1
nsv470680	Chr.1:1070426 - 1378635 on Build GRCh38	Loss	MIR6808 AURKAIP1 SDF4 ACAP3 DVL1 MXRA8 CPSF3L CPTP TNFRSF4 SCNN1D TNFRSF18 MIR200B FAM132A UBE2J2 MIR200A RNF223 C1orf159 MIR6727 TAS1R3 LINC01342 B3GALT6 TTLL10 MIR6726 MIR429 TTLL10-AS1 PUSL1
dgv6n100	Chr.1:1301750 - 1362354 on Build GRCh38	Gain+Loss	MIR6808 ACAP3 DVL1 MXRA8 CPSF3L MIR6727 CPTP TAS1R3 PUSL1
esv3584992	Chr.1:1314419 - 1330342 on Build GRCh38	Gain	CPSF3L CPTP
nsv1160788	Chr.1:1282706 - 1376336 on Build GRCh38	Deletion	MIR6808 AURKAIP1 SCNN1D ACAP3 DVL1 MXRA8 CPSF3L MIR6727 MIR6726 CPTP TAS1R3 PUSL1
nsv1160772	Chr.1:1027585 - 1333467 on Build GRCh38	Duplication	SDF4 ACAP3 CPSF3L AGRN CPTP TNFRSF4 SCNN1D TNFRSF18 MIR200B FAM132A UBE2J2 MIR200A LOC105378948 RNF223 C1orf159 MIR6727 LOC100288175 TAS1R3 LINC01342 B3GALT6 TTLL10 MIR6726 MIR429 TTLL10-AS1 PUSL1
nsv10161	Chr.1:776731 - 1777210 on Build GRCh38	Gain+Loss	AURKAIP1 MMP23B DVL1 MXRA8 LOC148413 NADK MIB2 SLC35E2B TMEM240 ATAD3A TNFRSF4 SCNN1D KLHL17 NOC2L TNFRSF18 MMP23A FNDC10 LINC01128 LOC107985729 PLEKHN1 ATAD3C FAM41C MIR200A RNF223 C1orf159 MIR6727 LOC100288175 TMEM88B MRPL20 LOC107985728 LINC00115 SLC35E2 TTLL10 MIR429 CDK11A PUSL1 CCNL2 VWA1 MIR6808 SDF4 ACAP3 CPSF3L FAM87B LOC100287934 AGRN CPTP SSU72 MIR200B LOC284600 HES4 LOC100130417 FAM132A ANKRD65 UBE2J2 LOC105378948 PERM1 LOC100288069 CDK11B ISG15 ATAD3B TAS1R3 LINC01342 B3GALT6 LOC102724312 MIR6726 TTLL10-AS1 SAMD11
esv3890636	Chr.1:1304555 - 1353203 on Build GRCh38	Loss	MIR6808 ACAP3 DVL1 MXRA8 CPSF3L MIR6727 CPTP TAS1R3 PUSL1
nsv1000169	Chr.1:1281678 - 1362354 on Build GRCh38	Gain	MIR6808 SCNN1D ACAP3 DVL1 MXRA8 CPSF3L MIR6727 MIR6726 CPTP TAS1R3 PUSL1
nsv950452	Chr.1:1106921 - 1637538 on Build GRCh38	Deletion	MIR6808 AURKAIP1 SDF4 MMP23B ACAP3 DVL1 MXRA8 LOC148413 CPSF3L MIB2 CPTP TMEM240 ATAD3A TNFRSF4 SCNN1D SSU72 TNFRSF18 FNDC10 LOC107985729 MIR200B ATAD3C FAM132A ANKRD65 UBE2J2 MIR200A CDK11B C1orf159 MIR6727 TMEM88B ATAD3B TAS1R3 LINC01342 MRPL20 B3GALT6 LOC102724312 TTLL10 MIR6726 MIR429 TTLL10-AS1 PUSL1 CCNL2 VWA1
esv2758912	Chr.1:1263940 - 1384492 on Build GRCh38	Loss	MIR6808 AURKAIP1 ACAP3 DVL1 MXRA8 UBE2J2 CPSF3L MIR6727 CPTP TAS1R3 SCNN1D MIR6726 PUSL1
dgv2n67	Chr.1:877618 - 1426500 on Build GRCh38	Gain	MIR6808 AURKAIP1 SDF4 ACAP3 DVL1 MXRA8 LOC148413 CPSF3L AGRN CPTP TNFRSF4 SCNN1D KLHL17 NOC2L TNFRSF18 PLEKHN1 MIR200B LOC284600 HES4 LOC100130417 FAM132A ANKRD65 UBE2J2 MIR200A LOC105378948 PERM1 RNF223 ISG15 C1orf159 MIR6727 LOC100288175 TMEM88B TAS1R3 LINC01342 MRPL20 LOC107985728 B3GALT6 TTLL10 MIR6726 MIR429 TTLL10-AS1 SAMD11 PUSL1 CCNL2
nsv469848	Chr.1:1146082 - 1322235 on Build GRCh38	Gain	SDF4 ACAP3 FAM132A UBE2J2 MIR200A CPSF3L MIR6727 TNFRSF4 SCNN1D B3GALT6 TNFRSF18 TTLL10 MIR6726 MIR429 TTLL10-AS1 MIR200B PUSL1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA processing factor

Gene Ontology Categories:

Process(es)

snRNA processing
snRNA transcription from RNA polymerase II promoter

Function(s)

protein binding
hydrolase activity