Hs02918742_cn

• Gene Symbol: TNFRSF4
• Assay Reference Genome Location: Chr.1:1213630 on build GRCh38
• Cytoband: 1p36.33

Target Gene Details

• Entrez Gene ID: 7293
• Gene Name: TNF receptor superfamily member 4
• Gene Aliases: ACT35, CD134, IMD16, OX40, TXGP1L
• Location: Chr.1:1211326-1216812 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TNFRSF4	NM_003327.3			NP_003318.1
	XM_011542074.2	1	127	XP_011540376.1
	XM_011542075.2			XP_011540377.1
	XM_011542076.2	1	127	XP_011540378.1
	XM_017002231.1			XP_016857720.1
	XM_017002232.1			XP_016857721.1
	BC105070.1			AAI05071.1
	BC105072.1			AAI05073.1
	S76792.1			AAB33944.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv482937	Chr.1:10001 - 2368561 on Build GRCh38	Loss	ATAD3B MTND2P28 LOC100129534 SSU72 FNDC10 MIR6727 CCNL2 TMEM88B SDF4 ANKRD65 LOC100130417 LINC01128 GABRD PLEKHN1 FAM138A ISG15 WASH7P CPSF3L CDK11B LOC100506504 LOC105378592 LOC101928626 CALML6 LOC105378948 AURKAIP1 LOC100288069 CFAP74 NOC2L MIR429 SKI LOC105378947 FAM41C LOC284600 LOC107984841 MIR6723 SCNN1D LOC105378949 ACAP3 DVL1 LOC100133331 MIR6808 MIB2 LOC107985729 LOC105378591 FAM132A ATAD3C TAS1R3 HES4 LINC01342 TMEM240 TTLL10 MIR6726 LOC107985728 MMP23A LOC102724312 LOC100134822 DDX11L1 MMP23B MTND1P23 MIR6859-1 LOC729737 SLC35E2 PUSL1 LOC148413 RNF223 FAM87B B3GALT6 CDK11A TNFRSF4 PERM1 VWA1 MIR1302-2 LOC100132287 TTLL10-AS1 TMEM52 SLC35E2B LOC105378589 MIR6859-2 KLHL17 LINC00115 NADK PRKCZ FAAP20 TNFRSF18 SAMD11 MORN1 LOC100288175 LOC100287934 LOC102725121 MRPL20 UBE2J2 C1orf159 CPTP GNB1 OR4F16 OR4F29 AGRN MIR200B ATAD3A OR4F5 MXRA8 MIR200A
nsv1003578	Chr.1:1068249 - 1282706 on Build GRCh38	Gain	TTLL10-AS1 UBE2J2 C1orf159 LOC105378948 FAM132A MIR200B RNF223 MIR429 B3GALT6 TNFRSF18 TNFRSF4 LINC01342 TTLL10 SDF4 SCNN1D MIR200A
nsv470680	Chr.1:1070426 - 1378635 on Build GRCh38	Loss	TTLL10-AS1 DVL1 MIR6808 AURKAIP1 FAM132A MIR6727 TAS1R3 MIR429 TNFRSF18 LINC01342 TTLL10 SDF4 MIR6726 UBE2J2 C1orf159 CPTP MIR200B PUSL1 RNF223 B3GALT6 MXRA8 TNFRSF4 CPSF3L SCNN1D ACAP3 MIR200A
nsv544956	Chr.1:1171093 - 1241217 on Build GRCh38	Loss	TTLL10-AS1 B3GALT6 TNFRSF18 TNFRSF4 TTLL10 SDF4
nsv544963	Chr.1:1206945 - 1214281 on Build GRCh38	Loss	TNFRSF18 TNFRSF4
nsv1160772	Chr.1:1027585 - 1333467 on Build GRCh38	Duplication	TTLL10-AS1 LOC105378948 FAM132A MIR6727 TAS1R3 MIR429 TNFRSF18 LINC01342 TTLL10 SDF4 LOC100288175 MIR6726 UBE2J2 C1orf159 CPTP AGRN MIR200B PUSL1 RNF223 B3GALT6 TNFRSF4 CPSF3L SCNN1D ACAP3 MIR200A
nsv428334	Chr.1:874371 - 1220569 on Build GRCh38	Gain	TTLL10-AS1 KLHL17 LOC105378948 NOC2L MIR429 HES4 TNFRSF18 LINC01342 TTLL10 SDF4 SAMD11 LOC100288175 FAM41C C1orf159 LOC107985728 LOC100130417 AGRN MIR200B LOC284600 PLEKHN1 RNF223 TNFRSF4 PERM1 ISG15 MIR200A
nsv10161	Chr.1:776731 - 1777210 on Build GRCh38	Gain+Loss	DVL1 ATAD3B MIR6808 MIB2 LOC107985729 SSU72 FAM132A ATAD3C FNDC10 MIR6727 TAS1R3 CCNL2 HES4 LINC01342 TMEM240 TMEM88B TTLL10 SDF4 MIR6726 ANKRD65 LOC107985728 MMP23A LOC102724312 MMP23B LOC100130417 LINC01128 SLC35E2 PUSL1 LOC148413 PLEKHN1 RNF223 FAM87B B3GALT6 CDK11A TNFRSF4 PERM1 VWA1 ISG15 CPSF3L CDK11B TTLL10-AS1 SLC35E2B KLHL17 LOC105378948 LINC00115 AURKAIP1 NADK LOC100288069 NOC2L MIR429 TNFRSF18 SAMD11 LOC100288175 LOC100287934 FAM41C MRPL20 UBE2J2 C1orf159 CPTP AGRN MIR200B LOC284600 ATAD3A MXRA8 SCNN1D ACAP3 MIR200A
nsv950452	Chr.1:1106921 - 1637538 on Build GRCh38	Deletion	TTLL10-AS1 DVL1 ATAD3B MIR6808 AURKAIP1 MIB2 LOC107985729 SSU72 FAM132A ATAD3C FNDC10 MIR6727 TAS1R3 CCNL2 MIR429 TNFRSF18 LINC01342 TMEM240 TMEM88B TTLL10 SDF4 MIR6726 MRPL20 UBE2J2 ANKRD65 C1orf159 CPTP LOC102724312 MMP23B MIR200B ATAD3A PUSL1 LOC148413 B3GALT6 MXRA8 TNFRSF4 VWA1 CPSF3L SCNN1D CDK11B ACAP3 MIR200A
nsv517709	Chr.1:817186 - 1275912 on Build GRCh38	Gain+Loss	TTLL10-AS1 KLHL17 LOC105378948 LINC00115 FAM132A NOC2L MIR429 HES4 TNFRSF18 LINC01342 TTLL10 SDF4 SAMD11 LOC100288175 FAM41C UBE2J2 C1orf159 LOC107985728 LOC100130417 LINC01128 AGRN MIR200B LOC284600 PLEKHN1 RNF223 FAM87B B3GALT6 TNFRSF4 PERM1 ISG15 MIR200A
nsv1160644	Chr.1:939652 - 1220663 on Build GRCh38	Deletion	TTLL10-AS1 LOC100288175 C1orf159 KLHL17 LOC105378948 AGRN MIR200B NOC2L PLEKHN1 RNF223 MIR429 HES4 TNFRSF18 TNFRSF4 LINC01342 PERM1 ISG15 TTLL10 SDF4 MIR200A SAMD11
dgv2n67	Chr.1:877618 - 1426500 on Build GRCh38	Gain	TTLL10-AS1 DVL1 KLHL17 MIR6808 LOC105378948 AURKAIP1 FAM132A MIR6727 TAS1R3 NOC2L CCNL2 MIR429 HES4 TNFRSF18 LINC01342 TMEM88B TTLL10 SDF4 SAMD11 LOC100288175 MIR6726 MRPL20 UBE2J2 ANKRD65 C1orf159 LOC107985728 CPTP LOC100130417 AGRN MIR200B LOC284600 PUSL1 LOC148413 PLEKHN1 RNF223 B3GALT6 MXRA8 TNFRSF4 PERM1 ISG15 CPSF3L SCNN1D ACAP3 MIR200A
nsv469848	Chr.1:1146082 - 1322235 on Build GRCh38	Gain	TTLL10-AS1 MIR6726 UBE2J2 FAM132A MIR200B MIR6727 PUSL1 MIR429 B3GALT6 TNFRSF18 TNFRSF4 TTLL10 CPSF3L SDF4 SCNN1D ACAP3 MIR200A

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

inflammatory response
immune response
multicellular organism development
positive regulation of B cell proliferation
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
T cell proliferation
regulation of cell proliferation
regulation of apoptotic process
positive regulation of MAPK cascade
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of transcription, DNA-templated
viral entry into host cell
positive regulation of immunoglobulin secretion
apoptotic signaling pathway

Function(s)

virus receptor activity
tumor necrosis factor-activated receptor activity