Hs03338997_cn

• Gene Symbol: CPSF3L
• Assay Reference Genome Location: Chr.1:1317629 on build GRCh38
• Cytoband: 1p36.33

Target Gene Details

• Entrez Gene ID: 54973
• Gene Name: cleavage and polyadenylation specific factor 3-like
• Gene Aliases: CPSF73L, INT11, INTS11, RC-68, RC68
• Location: Chr.1:1311585-1324687 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CPSF3L	NM_001256456.1			NP_001243385.1
	NM_001256460.1			NP_001243389.1
	NM_001256462.1			NP_001243391.1
	NM_001256463.1			NP_001243392.1
	NM_017871.5			NP_060341.2
	XM_011541647.1			XP_011539949.1
	XM_011541648.1			XP_011539950.1
	XM_011541650.1			XP_011539952.1
	XM_017001557.1			XP_016857046.1
	XM_017001558.1			XP_016857047.1
	AK021939.1			BAB13943.1
	AK023356.1			BAB14541.1
	AK056652.1
	AK058018.1
	AK092190.1
	AK291387.1
	AK297350.1
	AL136813.1			CAB66747.1
	BC000675.2			AAH00675.2
	BC007978.2			AAH07978.1
	BC008041.2			AAH08041.1
	BC020199.1			AAH20199.1
	CR533557.1			CAG38588.1
	DC295791.1
	DC299237.1
	DC299993.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv482937	Chr.1:10001 - 2368561 on Build GRCh38	Loss	KLHL17 MIR6859-1 CALML6 TNFRSF18 PRKCZ CDK11B MRPL20 LOC105378592 CFAP74 LOC100287934 MIR6808 FAM87B LOC100129534 MMP23B ISG15 MIR200B PERM1 MTND1P23 SLC35E2 LOC284600 TMEM240 NADK TMEM52 VWA1 C1orf159 LOC107985728 WASH7P B3GALT6 MMP23A MIR6726 LOC100130417 FAM138A GABRD MIB2 MIR1302-2 FAM41C LOC100506504 LOC100288069 ACAP3 ATAD3A LOC105378947 FNDC10 LOC100288175 MIR6859-2 LOC102724312 LINC01342 LOC105378589 SCNN1D FAM132A SKI FAAP20 MTND2P28 DVL1 LOC105378591 MIR200A TNFRSF4 LOC107985729 LOC148413 ATAD3B TTLL10-AS1 SDF4 SAMD11 CPSF3L ATAD3C LOC100133331 LOC105378948 LOC107984841 DDX11L1 OR4F16 RNF223 CPTP TMEM88B LOC729737 SLC35E2B LINC00115 TTLL10 MIR429 PUSL1 AURKAIP1 SSU72 MORN1 UBE2J2 AGRN PLEKHN1 LOC101928626 LOC100134822 OR4F29 LOC102725121 MIR6723 MXRA8 ANKRD65 CDK11A LOC100132287 TAS1R3 OR4F5 LOC105378949 CCNL2 HES4 LINC01128 GNB1 MIR6727 NOC2L
nsv544971	Chr.1:1294063 - 1351426 on Build GRCh38	Loss	MIR6808 CPTP ACAP3 CPSF3L PUSL1 TAS1R3 MIR6727 MIR6726 DVL1
nsv544969	Chr.1:1290683 - 1374597 on Build GRCh38	Loss	MIR6808 CPTP SCNN1D ACAP3 CPSF3L PUSL1 AURKAIP1 TAS1R3 MIR6727 MIR6726 DVL1 MXRA8
nsv997291	Chr.1:1306835 - 1376336 on Build GRCh38	Gain	MIR6808 CPTP ACAP3 CPSF3L PUSL1 AURKAIP1 TAS1R3 MIR6727 DVL1 MXRA8
nsv470680	Chr.1:1070426 - 1378635 on Build GRCh38	Loss	UBE2J2 SDF4 CPSF3L TNFRSF18 ACAP3 RNF223 MXRA8 MIR6808 CPTP LINC01342 SCNN1D FAM132A TAS1R3 MIR200B DVL1 TTLL10 MIR200A TNFRSF4 MIR429 PUSL1 AURKAIP1 C1orf159 TTLL10-AS1 MIR6727 B3GALT6 MIR6726
dgv6n100	Chr.1:1301750 - 1362354 on Build GRCh38	Gain+Loss	MIR6808 CPTP ACAP3 CPSF3L PUSL1 TAS1R3 MIR6727 DVL1 MXRA8
esv3584992	Chr.1:1314419 - 1330342 on Build GRCh38	Gain	CPTP CPSF3L
nsv1160788	Chr.1:1282706 - 1376336 on Build GRCh38	Deletion	MIR6808 CPTP SCNN1D ACAP3 CPSF3L PUSL1 AURKAIP1 TAS1R3 MIR6727 MIR6726 DVL1 MXRA8
nsv1160772	Chr.1:1027585 - 1333467 on Build GRCh38	Duplication	UBE2J2 AGRN SDF4 CPSF3L TNFRSF18 ACAP3 LOC105378948 LOC100288175 RNF223 CPTP LINC01342 SCNN1D FAM132A TAS1R3 MIR200B TTLL10 MIR200A TNFRSF4 MIR429 PUSL1 C1orf159 TTLL10-AS1 MIR6727 B3GALT6 MIR6726
nsv10161	Chr.1:776731 - 1777210 on Build GRCh38	Gain+Loss	KLHL17 SDF4 SAMD11 CPSF3L ATAD3C TNFRSF18 CDK11B MRPL20 LOC105378948 RNF223 LOC100287934 MIR6808 CPTP FAM87B TMEM88B MMP23B ISG15 SLC35E2B MIR200B PERM1 SLC35E2 LINC00115 TTLL10 LOC284600 TMEM240 MIR429 PUSL1 NADK VWA1 AURKAIP1 C1orf159 LOC107985728 SSU72 B3GALT6 MMP23A MIR6726 LOC100130417 UBE2J2 AGRN PLEKHN1 MIB2 FAM41C LOC100288069 ACAP3 ATAD3A FNDC10 LOC100288175 MXRA8 ANKRD65 LOC102724312 CDK11A LINC01342 SCNN1D FAM132A TAS1R3 CCNL2 DVL1 MIR200A HES4 TNFRSF4 LOC107985729 LOC148413 LINC01128 ATAD3B TTLL10-AS1 MIR6727 NOC2L
esv3890636	Chr.1:1304555 - 1353203 on Build GRCh38	Loss	MIR6808 CPTP ACAP3 CPSF3L PUSL1 TAS1R3 MIR6727 DVL1 MXRA8
nsv1000169	Chr.1:1281678 - 1362354 on Build GRCh38	Gain	MIR6808 CPTP SCNN1D ACAP3 CPSF3L PUSL1 TAS1R3 MIR6727 MIR6726 DVL1 MXRA8
nsv950452	Chr.1:1106921 - 1637538 on Build GRCh38	Deletion	UBE2J2 SDF4 CPSF3L MIB2 ATAD3C TNFRSF18 CDK11B MRPL20 ACAP3 ATAD3A FNDC10 MXRA8 MIR6808 ANKRD65 CPTP LOC102724312 TMEM88B LINC01342 MMP23B SCNN1D FAM132A TAS1R3 MIR200B CCNL2 DVL1 TTLL10 MIR200A TNFRSF4 LOC107985729 LOC148413 TMEM240 MIR429 PUSL1 ATAD3B VWA1 AURKAIP1 C1orf159 SSU72 TTLL10-AS1 MIR6727 B3GALT6 MIR6726
esv2758912	Chr.1:1263940 - 1384492 on Build GRCh38	Loss	MIR6808 UBE2J2 CPTP SCNN1D CPSF3L TAS1R3 DVL1 ACAP3 PUSL1 AURKAIP1 MIR6727 MIR6726 MXRA8
dgv2n67	Chr.1:877618 - 1426500 on Build GRCh38	Gain	UBE2J2 AGRN KLHL17 SDF4 PLEKHN1 SAMD11 CPSF3L TNFRSF18 MRPL20 ACAP3 LOC105378948 LOC100288175 RNF223 MXRA8 MIR6808 ANKRD65 CPTP TMEM88B LINC01342 ISG15 SCNN1D FAM132A TAS1R3 MIR200B PERM1 CCNL2 DVL1 TTLL10 MIR200A HES4 LOC284600 TNFRSF4 LOC148413 MIR429 PUSL1 AURKAIP1 C1orf159 LOC107985728 TTLL10-AS1 MIR6727 B3GALT6 MIR6726 LOC100130417 NOC2L
nsv469848	Chr.1:1146082 - 1322235 on Build GRCh38	Gain	UBE2J2 SDF4 SCNN1D FAM132A CPSF3L MIR200B TNFRSF18 TTLL10 MIR200A TNFRSF4 MIR429 ACAP3 PUSL1 TTLL10-AS1 MIR6727 B3GALT6 MIR6726

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA processing factor

Gene Ontology Categories:

Process(es)

snRNA processing
snRNA transcription from RNA polymerase II promoter

Function(s)

protein binding
hydrolase activity