Hs03347543_cn

• Gene Symbol: TNFRSF4
• Assay Reference Genome Location: Chr.1:1215613 on build GRCh38
• Cytoband: 1p36.33

Target Gene Details

• Entrez Gene ID: 7293
• Gene Name: TNF receptor superfamily member 4
• Gene Aliases: ACT35, CD134, IMD16, OX40, TXGP1L
• Location: Chr.1:1211326-1216812 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TNFRSF4	XM_017002231.1	1	1200	XP_016857720.1
	XM_017002232.1	1	1200	XP_016857721.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1160772	Chr.1:1027585 - 1333467 on Build GRCh38	Duplication	CPTP TNFRSF4 TTLL10-AS1 ACAP3 MIR6726 UBE2J2 PUSL1 LOC105378948 RNF223 TNFRSF18 C1orf159 MIR429 SCNN1D LOC100288175 MIR6727 CPSF3L MIR200B B3GALT6 AGRN LINC01342 TAS1R3 FAM132A MIR200A TTLL10 SDF4
nsv428334	Chr.1:874371 - 1220569 on Build GRCh38	Gain	TNFRSF4 TTLL10-AS1 LOC107985728 LOC105378948 RNF223 TNFRSF18 SAMD11 C1orf159 HES4 MIR429 LOC100288175 KLHL17 PLEKHN1 FAM41C MIR200B LOC284600 PERM1 LOC100130417 AGRN ISG15 LINC01342 MIR200A TTLL10 SDF4 NOC2L
nsv10161	Chr.1:776731 - 1777210 on Build GRCh38	Gain+Loss	CPTP TNFRSF4 TTLL10-AS1 VWA1 LOC107985728 ACAP3 AURKAIP1 MIR6726 MMP23B RNF223 LOC107985729 TNFRSF18 TMEM88B SAMD11 FNDC10 LINC01128 MXRA8 MIR6727 CPSF3L LOC148413 FAM41C MIR200B LOC284600 B3GALT6 ISG15 LOC102724312 LINC01342 FAM132A MRPL20 ANKRD65 ATAD3B CDK11B NADK SLC35E2B LINC00115 LOC100288069 CCNL2 SLC35E2 CDK11A UBE2J2 PUSL1 FAM87B LOC105378948 SSU72 DVL1 LOC100287934 C1orf159 HES4 MIR429 SCNN1D LOC100288175 ATAD3C KLHL17 PLEKHN1 ATAD3A PERM1 LOC100130417 AGRN TAS1R3 TMEM240 MMP23A MIR6808 MIR200A MIB2 TTLL10 SDF4 NOC2L
nsv482937	Chr.1:10001 - 2368561 on Build GRCh38	Loss	CPTP LOC105378591 CALML6 LOC101928626 ACAP3 RNF223 LOC100133331 TMEM88B SAMD11 LOC102725121 MIR6727 CPSF3L MIR200B LOC284600 B3GALT6 SKI LOC102724312 OR4F5 MRPL20 LOC105378592 ANKRD65 MTND1P23 CDK11B LOC100288069 CCNL2 SLC35E2 LOC105378949 PUSL1 FAM87B DDX11L1 SSU72 DVL1 HES4 MIR429 GNB1 SCNN1D WASH7P MIR1302-2 ATAD3C KLHL17 FAM138A PLEKHN1 OR4F16 LOC107984841 MMP23A MIR200A MIB2 NOC2L TNFRSF4 TTLL10-AS1 VWA1 LOC107985728 LOC100506504 AURKAIP1 MIR6726 MMP23B MIR6859-1 LOC107985729 TNFRSF18 FAAP20 FNDC10 LINC01128 LOC100134822 MXRA8 LOC729737 LOC148413 FAM41C MTND2P28 CFAP74 ISG15 LINC01342 FAM132A GABRD MIR6723 ATAD3B MIR6859-2 NADK SLC35E2B LINC00115 LOC100129534 CDK11A UBE2J2 LOC105378948 LOC105378589 TMEM52 PRKCZ LOC100287934 C1orf159 OR4F29 LOC105378947 LOC100288175 MORN1 ATAD3A PERM1 LOC100130417 AGRN LOC100132287 TAS1R3 TMEM240 MIR6808 TTLL10 SDF4
nsv950452	Chr.1:1106921 - 1637538 on Build GRCh38	Deletion	CPTP TNFRSF4 TTLL10-AS1 VWA1 CCNL2 ACAP3 AURKAIP1 MIR6726 UBE2J2 PUSL1 MMP23B SSU72 DVL1 LOC107985729 TNFRSF18 TMEM88B FNDC10 C1orf159 MXRA8 MIR429 SCNN1D MIR6727 ATAD3C CPSF3L ATAD3A LOC148413 MIR200B B3GALT6 LOC102724312 LINC01342 TAS1R3 FAM132A TMEM240 MRPL20 ANKRD65 MIR6808 ATAD3B MIR200A MIB2 TTLL10 SDF4 CDK11B
nsv517709	Chr.1:817186 - 1275912 on Build GRCh38	Gain+Loss	TNFRSF4 LINC00115 TTLL10-AS1 LOC107985728 UBE2J2 FAM87B LOC105378948 RNF223 TNFRSF18 SAMD11 LINC01128 C1orf159 HES4 MIR429 LOC100288175 KLHL17 PLEKHN1 FAM41C MIR200B LOC284600 PERM1 B3GALT6 LOC100130417 AGRN ISG15 LINC01342 FAM132A MIR200A TTLL10 SDF4 NOC2L
nsv1160644	Chr.1:939652 - 1220663 on Build GRCh38	Deletion	MIR429 TNFRSF4 LOC100288175 TTLL10-AS1 KLHL17 PLEKHN1 MIR200B PERM1 AGRN ISG15 LOC105378948 LINC01342 RNF223 TNFRSF18 MIR200A SAMD11 C1orf159 TTLL10 SDF4 HES4 NOC2L
dgv2n67	Chr.1:877618 - 1426500 on Build GRCh38	Gain	CPTP TNFRSF4 TTLL10-AS1 CCNL2 LOC107985728 ACAP3 AURKAIP1 MIR6726 UBE2J2 PUSL1 LOC105378948 RNF223 DVL1 TNFRSF18 TMEM88B SAMD11 C1orf159 HES4 MXRA8 MIR429 SCNN1D LOC100288175 MIR6727 KLHL17 CPSF3L PLEKHN1 LOC148413 MIR200B LOC284600 PERM1 B3GALT6 LOC100130417 AGRN ISG15 LINC01342 TAS1R3 FAM132A MRPL20 ANKRD65 MIR6808 MIR200A TTLL10 SDF4 NOC2L
nsv1003578	Chr.1:1068249 - 1282706 on Build GRCh38	Gain	MIR429 TNFRSF4 SCNN1D TTLL10-AS1 MIR200B B3GALT6 UBE2J2 LOC105378948 LINC01342 FAM132A RNF223 TNFRSF18 MIR200A C1orf159 TTLL10 SDF4
nsv470680	Chr.1:1070426 - 1378635 on Build GRCh38	Loss	CPTP TNFRSF4 TTLL10-AS1 ACAP3 AURKAIP1 MIR6726 UBE2J2 PUSL1 RNF223 DVL1 TNFRSF18 C1orf159 MXRA8 MIR429 SCNN1D MIR6727 CPSF3L MIR200B B3GALT6 LINC01342 TAS1R3 FAM132A MIR6808 MIR200A TTLL10 SDF4
nsv544956	Chr.1:1171093 - 1241217 on Build GRCh38	Loss	TNFRSF4 TTLL10-AS1 TNFRSF18 TTLL10 B3GALT6 SDF4
nsv469848	Chr.1:1146082 - 1322235 on Build GRCh38	Gain	MIR429 TNFRSF4 SCNN1D MIR6727 TTLL10-AS1 CPSF3L MIR200B ACAP3 MIR6726 B3GALT6 UBE2J2 PUSL1 FAM132A TNFRSF18 MIR200A TTLL10 SDF4

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

inflammatory response
immune response
multicellular organism development
positive regulation of B cell proliferation
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
T cell proliferation
regulation of cell proliferation
regulation of apoptotic process
positive regulation of MAPK cascade
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of transcription, DNA-templated
viral entry into host cell
positive regulation of immunoglobulin secretion
apoptotic signaling pathway

Function(s)

virus receptor activity
tumor necrosis factor-activated receptor activity