Hs03354605_cn

• Gene Symbol: TNFRSF4
• Assay Reference Genome Location: Chr.1:1214430 on build GRCh38
• Cytoband: 1p36.33

Target Gene Details

• Entrez Gene ID: 7293
• Gene Name: TNF receptor superfamily member 4
• Gene Aliases: ACT35, CD134, IMD16, OX40, TXGP1L
• Location: Chr.1:1211326-1216812 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TNFRSF4	XM_011542075.2	1	206	XP_011540377.1
	XM_017002231.1			XP_016857720.1
	XM_017002232.1			XP_016857721.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1160772	Chr.1:1027585 - 1333467 on Build GRCh38	Duplication	TNFRSF4 LOC105378948 SDF4 TTLL10-AS1 UBE2J2 SCNN1D PUSL1 TNFRSF18 LINC01342 RNF223 B3GALT6 TAS1R3 ACAP3 MIR6726 TTLL10 MIR429 MIR200B FAM132A LOC100288175 MIR6727 CPSF3L AGRN CPTP MIR200A C1orf159
nsv428334	Chr.1:874371 - 1220569 on Build GRCh38	Gain	HES4 TNFRSF4 LOC105378948 SDF4 FAM41C PERM1 TTLL10-AS1 LOC284600 NOC2L TNFRSF18 LINC01342 LOC100130417 RNF223 SAMD11 PLEKHN1 TTLL10 MIR429 MIR200B ISG15 LOC100288175 LOC107985728 KLHL17 AGRN MIR200A C1orf159
nsv10161	Chr.1:776731 - 1777210 on Build GRCh38	Gain+Loss	HES4 CDK11B LOC105378948 SDF4 PERM1 MMP23B TMEM240 MIB2 MMP23A UBE2J2 VWA1 LOC284600 NOC2L TMEM88B LOC100130417 RNF223 SSU72 LOC107985729 B3GALT6 LOC102724312 NADK ATAD3C LINC00115 FAM87B TTLL10 MIR200B ISG15 CPTP MIR200A SLC35E2 C1orf159 TNFRSF4 FAM41C LOC148413 ATAD3A LOC100288069 FNDC10 TTLL10-AS1 AURKAIP1 SCNN1D PUSL1 TNFRSF18 LINC01342 SLC35E2B ATAD3B SAMD11 TAS1R3 ACAP3 LOC100287934 DVL1 MIR6726 PLEKHN1 MRPL20 MIR6808 ANKRD65 MXRA8 MIR429 FAM132A LOC100288175 LOC107985728 MIR6727 KLHL17 CPSF3L AGRN CCNL2 LINC01128 CDK11A
nsv482937	Chr.1:10001 - 2368561 on Build GRCh38	Loss	CDK11B LOC105378948 SDF4 CALML6 TMEM240 MMP23A UBE2J2 VWA1 NOC2L TMEM88B LOC100130417 TMEM52 SSU72 LOC107985729 B3GALT6 FAAP20 OR4F16 MIR1302-2 NADK ATAD3C MTND2P28 LINC00115 LOC107984841 LOC100132287 MIR200B ISG15 LOC100134822 SKI CPTP MIR200A SLC35E2 LOC100506504 TNFRSF4 LOC105378591 ATAD3A LOC100288069 WASH7P PUSL1 LOC105378947 MORN1 SLC35E2B ATAD3B SAMD11 ACAP3 OR4F29 LOC105378949 DVL1 PLEKHN1 MIR6808 MIR429 FAM132A LOC100288175 KLHL17 CPSF3L LOC105378589 AGRN LINC01128 HES4 PERM1 MMP23B LOC101928626 DDX11L1 MIB2 LOC284600 FAM138A MIR6723 RNF223 LOC102724312 LOC100129534 FAM87B TTLL10 LOC102725121 C1orf159 FAM41C PRKCZ LOC100133331 LOC148413 FNDC10 MIR6859-2 TTLL10-AS1 AURKAIP1 GABRD SCNN1D TNFRSF18 LINC01342 MTND1P23 TAS1R3 LOC100287934 LOC105378592 LOC729737 CFAP74 MIR6726 MRPL20 ANKRD65 MXRA8 LOC107985728 MIR6727 GNB1 CCNL2 MIR6859-1 CDK11A OR4F5
nsv950452	Chr.1:1106921 - 1637538 on Build GRCh38	Deletion	TNFRSF4 CDK11B SDF4 LOC148413 ATAD3A FNDC10 TTLL10-AS1 AURKAIP1 MMP23B TMEM240 MIB2 UBE2J2 VWA1 SCNN1D PUSL1 TNFRSF18 TMEM88B LINC01342 SSU72 ATAD3B LOC107985729 B3GALT6 TAS1R3 ACAP3 LOC102724312 DVL1 ATAD3C MIR6726 MRPL20 MIR6808 ANKRD65 MXRA8 TTLL10 MIR429 MIR200B FAM132A MIR6727 CPSF3L CPTP CCNL2 MIR200A C1orf159
nsv517709	Chr.1:817186 - 1275912 on Build GRCh38	Gain+Loss	HES4 TNFRSF4 LOC105378948 SDF4 FAM41C PERM1 TTLL10-AS1 UBE2J2 LOC284600 NOC2L TNFRSF18 LINC01342 LOC100130417 RNF223 SAMD11 B3GALT6 PLEKHN1 LINC00115 FAM87B TTLL10 MIR429 MIR200B ISG15 FAM132A LOC100288175 LOC107985728 KLHL17 AGRN LINC01128 MIR200A C1orf159
nsv1160644	Chr.1:939652 - 1220663 on Build GRCh38	Deletion	HES4 TNFRSF4 LOC105378948 SDF4 PERM1 TTLL10-AS1 PLEKHN1 TTLL10 MIR429 MIR200B ISG15 NOC2L TNFRSF18 LOC100288175 LINC01342 KLHL17 RNF223 AGRN MIR200A SAMD11 C1orf159
dgv2n67	Chr.1:877618 - 1426500 on Build GRCh38	Gain	HES4 TNFRSF4 LOC105378948 SDF4 LOC148413 PERM1 TTLL10-AS1 AURKAIP1 UBE2J2 SCNN1D PUSL1 LOC284600 NOC2L TNFRSF18 TMEM88B LINC01342 LOC100130417 RNF223 SAMD11 B3GALT6 TAS1R3 ACAP3 DVL1 MIR6726 PLEKHN1 MRPL20 MIR6808 ANKRD65 MXRA8 TTLL10 MIR429 MIR200B ISG15 FAM132A LOC100288175 LOC107985728 MIR6727 KLHL17 CPSF3L AGRN CPTP CCNL2 MIR200A C1orf159
nsv1003578	Chr.1:1068249 - 1282706 on Build GRCh38	Gain	TNFRSF4 LOC105378948 SDF4 TTLL10-AS1 TTLL10 MIR429 UBE2J2 SCNN1D MIR200B FAM132A TNFRSF18 LINC01342 RNF223 MIR200A B3GALT6 C1orf159
nsv470680	Chr.1:1070426 - 1378635 on Build GRCh38	Loss	TNFRSF4 SDF4 TTLL10-AS1 AURKAIP1 UBE2J2 SCNN1D PUSL1 TNFRSF18 LINC01342 RNF223 B3GALT6 TAS1R3 ACAP3 DVL1 MIR6726 MIR6808 MXRA8 TTLL10 MIR429 MIR200B FAM132A MIR6727 CPSF3L CPTP MIR200A C1orf159
nsv544956	Chr.1:1171093 - 1241217 on Build GRCh38	Loss	TTLL10 TNFRSF4 SDF4 TNFRSF18 TTLL10-AS1 B3GALT6
nsv469848	Chr.1:1146082 - 1322235 on Build GRCh38	Gain	TNFRSF4 SDF4 MIR6726 TTLL10-AS1 TTLL10 MIR429 UBE2J2 SCNN1D PUSL1 MIR200B FAM132A TNFRSF18 MIR6727 CPSF3L MIR200A B3GALT6 ACAP3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

inflammatory response
immune response
multicellular organism development
positive regulation of B cell proliferation
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
T cell proliferation
regulation of cell proliferation
regulation of apoptotic process
positive regulation of MAPK cascade
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of transcription, DNA-templated
viral entry into host cell
positive regulation of immunoglobulin secretion
apoptotic signaling pathway

Function(s)

virus receptor activity
tumor necrosis factor-activated receptor activity