Hs03366043_cn

• Gene Symbol: TNFRSF4
• Assay Reference Genome Location: Chr.1:1216341 on build GRCh38
• Cytoband: 1p36.33

Target Gene Details

• Entrez Gene ID: 7293
• Gene Name: TNF receptor superfamily member 4
• Gene Aliases: ACT35, CD134, IMD16, OX40, TXGP1L
• Location: Chr.1:1211326-1216812 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TNFRSF4	XM_017002231.1	1	472	XP_016857720.1
	XM_017002232.1	1	472	XP_016857721.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1160772	Chr.1:1027585 - 1333467 on Build GRCh38	Duplication	UBE2J2 TNFRSF18 ACAP3 CPTP MIR200B SDF4 LOC105378948 FAM132A B3GALT6 TAS1R3 MIR200A AGRN TNFRSF4 LINC01342 MIR6726 TTLL10-AS1 MIR429 C1orf159 SCNN1D MIR6727 PUSL1 LOC100288175 TTLL10 CPSF3L RNF223
nsv428334	Chr.1:874371 - 1220569 on Build GRCh38	Gain	TNFRSF18 LOC107985728 MIR200B PLEKHN1 SDF4 ISG15 LOC105378948 LOC100130417 MIR200A AGRN TNFRSF4 SAMD11 LINC01342 FAM41C PERM1 TTLL10-AS1 MIR429 C1orf159 LOC100288175 LOC284600 KLHL17 TTLL10 HES4 RNF223 NOC2L
nsv10161	Chr.1:776731 - 1777210 on Build GRCh38	Gain+Loss	ANKRD65 ATAD3A CDK11B LOC107985728 FAM87B ATAD3B PLEKHN1 SDF4 DVL1 FAM132A LOC100130417 B3GALT6 TAS1R3 LOC100288069 AGRN TNFRSF4 ATAD3C SAMD11 LINC01342 FAM41C SLC35E2 PERM1 MIR6726 NADK TTLL10-AS1 MIR429 SSU72 SCNN1D PUSL1 LOC107985729 CCNL2 LOC284600 MXRA8 HES4 MIR6808 SLC35E2B MMP23A UBE2J2 MRPL20 TNFRSF18 TMEM88B ACAP3 MIB2 CPTP FNDC10 MIR200B ISG15 LINC01128 LOC105378948 VWA1 LOC102724312 LOC148413 LOC100287934 MIR200A TMEM240 LINC00115 MMP23B C1orf159 MIR6727 LOC100288175 KLHL17 AURKAIP1 TTLL10 CPSF3L RNF223 NOC2L CDK11A
nsv482937	Chr.1:10001 - 2368561 on Build GRCh38	Loss	OR4F29 ATAD3A CDK11B LOC107985728 ATAD3B LOC105378949 MIR6859-1 PLEKHN1 OR4F5 FAM132A LOC100506504 TAS1R3 LOC100288069 AGRN CFAP74 MIR6723 MIR1302-2 TNFRSF4 FAAP20 ATAD3C SAMD11 LINC01342 FAM41C PERM1 MIR6726 NADK PUSL1 LOC107985729 CCNL2 OR4F16 MXRA8 MTND1P23 LOC105378947 HES4 MMP23A UBE2J2 TNFRSF18 GABRD TMEM88B ACAP3 LOC100129534 MIB2 MIR200B LOC105378591 VWA1 LOC102724312 LOC148413 MTND2P28 LOC101928626 LINC00115 MMP23B LOC105378589 MIR6727 MORN1 WASH7P CPSF3L CDK11A ANKRD65 CALML6 LOC100132287 MIR6859-2 FAM87B SDF4 DVL1 LOC100130417 DDX11L1 B3GALT6 SLC35E2 LOC729737 TTLL10-AS1 MIR429 SSU72 SCNN1D LOC284600 TMEM52 MIR6808 LOC100133331 SLC35E2B LOC107984841 LOC102725121 MRPL20 CPTP SKI FNDC10 FAM138A LOC100134822 ISG15 LINC01128 GNB1 LOC105378948 LOC100287934 MIR200A TMEM240 C1orf159 LOC100288175 KLHL17 LOC105378592 AURKAIP1 TTLL10 RNF223 NOC2L PRKCZ
nsv950452	Chr.1:1106921 - 1637538 on Build GRCh38	Deletion	ANKRD65 UBE2J2 MRPL20 TNFRSF18 TMEM88B ACAP3 MIB2 ATAD3A CDK11B CPTP FNDC10 ATAD3B MIR200B SDF4 DVL1 VWA1 LOC102724312 LOC148413 FAM132A B3GALT6 TAS1R3 MIR200A TMEM240 TNFRSF4 MMP23B ATAD3C LINC01342 MIR6726 TTLL10-AS1 MIR429 C1orf159 SSU72 SCNN1D MIR6727 PUSL1 LOC107985729 CCNL2 MXRA8 AURKAIP1 TTLL10 CPSF3L MIR6808
nsv517709	Chr.1:817186 - 1275912 on Build GRCh38	Gain+Loss	UBE2J2 TNFRSF18 LOC107985728 FAM87B MIR200B PLEKHN1 SDF4 ISG15 LINC01128 LOC105378948 FAM132A LOC100130417 B3GALT6 MIR200A AGRN LINC00115 TNFRSF4 SAMD11 LINC01342 FAM41C PERM1 TTLL10-AS1 MIR429 C1orf159 LOC100288175 LOC284600 KLHL17 TTLL10 HES4 RNF223 NOC2L
nsv1160644	Chr.1:939652 - 1220663 on Build GRCh38	Deletion	TNFRSF4 SAMD11 LINC01342 TNFRSF18 PERM1 TTLL10-AS1 MIR429 C1orf159 LOC100288175 MIR200B PLEKHN1 KLHL17 SDF4 ISG15 LOC105378948 TTLL10 HES4 MIR200A RNF223 NOC2L AGRN
dgv2n67	Chr.1:877618 - 1426500 on Build GRCh38	Gain	ANKRD65 UBE2J2 MRPL20 TNFRSF18 TMEM88B ACAP3 LOC107985728 CPTP MIR200B PLEKHN1 SDF4 ISG15 DVL1 LOC105378948 LOC148413 FAM132A LOC100130417 B3GALT6 TAS1R3 MIR200A AGRN TNFRSF4 SAMD11 LINC01342 PERM1 MIR6726 TTLL10-AS1 MIR429 C1orf159 SCNN1D MIR6727 PUSL1 LOC100288175 CCNL2 LOC284600 MXRA8 KLHL17 AURKAIP1 TTLL10 HES4 CPSF3L MIR6808 RNF223 NOC2L
nsv1003578	Chr.1:1068249 - 1282706 on Build GRCh38	Gain	TNFRSF4 UBE2J2 LINC01342 TNFRSF18 TTLL10-AS1 MIR429 C1orf159 SCNN1D MIR200B SDF4 LOC105378948 FAM132A TTLL10 B3GALT6 MIR200A RNF223
nsv470680	Chr.1:1070426 - 1378635 on Build GRCh38	Loss	UBE2J2 TNFRSF18 ACAP3 CPTP MIR200B SDF4 DVL1 FAM132A B3GALT6 TAS1R3 MIR200A TNFRSF4 LINC01342 MIR6726 TTLL10-AS1 MIR429 C1orf159 SCNN1D MIR6727 PUSL1 MXRA8 AURKAIP1 TTLL10 CPSF3L MIR6808 RNF223
nsv544956	Chr.1:1171093 - 1241217 on Build GRCh38	Loss	TNFRSF4 SDF4 TNFRSF18 TTLL10 B3GALT6 TTLL10-AS1
nsv469848	Chr.1:1146082 - 1322235 on Build GRCh38	Gain	TNFRSF4 UBE2J2 TNFRSF18 ACAP3 MIR6726 TTLL10-AS1 MIR429 SCNN1D MIR6727 PUSL1 MIR200B SDF4 FAM132A TTLL10 CPSF3L B3GALT6 MIR200A

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

inflammatory response
immune response
multicellular organism development
positive regulation of B cell proliferation
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
T cell proliferation
regulation of cell proliferation
regulation of apoptotic process
positive regulation of MAPK cascade
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of transcription, DNA-templated
viral entry into host cell
positive regulation of immunoglobulin secretion
apoptotic signaling pathway

Function(s)

virus receptor activity
tumor necrosis factor-activated receptor activity