Hs03368805_cn

• Gene Symbol: TNFRSF4
• Assay Reference Genome Location: Chr.1:1215287 on build GRCh38
• Cytoband: 1p36.33

Target Gene Details

• Entrez Gene ID: 7293
• Gene Name: TNF receptor superfamily member 4
• Gene Aliases: ACT35, CD134, IMD16, OX40, TXGP1L
• Location: Chr.1:1211326-1216812 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TNFRSF4	XM_017002231.1			XP_016857720.1
	XM_017002232.1			XP_016857721.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1160772	Chr.1:1027585 - 1333467 on Build GRCh38	Duplication	CPSF3L TTLL10-AS1 TTLL10 TNFRSF4 SCNN1D LOC105378948 C1orf159 MIR6726 ACAP3 PUSL1 RNF223 B3GALT6 LOC100288175 LINC01342 SDF4 MIR200B TNFRSF18 TAS1R3 CPTP MIR429 MIR200A UBE2J2 FAM132A MIR6727 AGRN
nsv428334	Chr.1:874371 - 1220569 on Build GRCh38	Gain	LOC100130417 KLHL17 TTLL10-AS1 TTLL10 TNFRSF4 PERM1 LOC105378948 NOC2L C1orf159 LOC107985728 RNF223 SAMD11 LOC100288175 LINC01342 SDF4 MIR200B LOC284600 TNFRSF18 HES4 MIR429 MIR200A FAM41C PLEKHN1 ISG15 AGRN
nsv10161	Chr.1:776731 - 1777210 on Build GRCh38	Gain+Loss	LOC102724312 LOC100130417 TMEM88B KLHL17 SSU72 LOC105378948 LOC100287934 ATAD3B ACAP3 LOC100288175 LINC01342 SDF4 LOC148413 NADK LOC284600 TNFRSF18 MIB2 HES4 LOC100288069 CDK11B CCNL2 VWA1 ATAD3A MIR6808 CDK11A DVL1 MIR200A FAM41C SLC35E2 MXRA8 MIR6727 AGRN LINC00115 FAM87B CPSF3L TTLL10-AS1 MRPL20 TTLL10 TNFRSF4 SCNN1D PERM1 TMEM240 NOC2L SLC35E2B C1orf159 LOC107985728 MIR6726 ANKRD65 PUSL1 RNF223 SAMD11 B3GALT6 MIR200B TAS1R3 CPTP MMP23A MIR429 ATAD3C FNDC10 PLEKHN1 LINC01128 UBE2J2 FAM132A MMP23B ISG15 LOC107985729 AURKAIP1
nsv482937	Chr.1:10001 - 2368561 on Build GRCh38	Loss	LOC102724312 TMEM88B SSU72 LOC105378948 LOC100287934 LOC107984841 CALML6 ATAD3B LOC105378591 DDX11L1 GNB1 SDF4 LOC284600 TNFRSF18 MIB2 HES4 LOC100288069 CDK11B ATAD3A CFAP74 MIR6808 DVL1 FAM41C PRKCZ MXRA8 SKI MIR1302-2 MIR6727 LOC729737 FAM87B TTLL10-AS1 MRPL20 TTLL10 TNFRSF4 PERM1 MTND2P28 SLC35E2B LOC107985728 MIR6726 PUSL1 SAMD11 B3GALT6 LOC100506504 MIR200B TAS1R3 LOC105378949 CPTP MMP23A LOC105378947 OR4F16 PLEKHN1 LOC100132287 MMP23B ISG15 LOC107985729 AURKAIP1 LOC101928626 LOC100130417 KLHL17 LOC105378589 FAM138A TMEM52 ACAP3 LOC100134822 LOC100288175 LINC01342 MIR6859-1 LOC148413 NADK MIR6859-2 MIR6723 CCNL2 VWA1 LOC100133331 FAAP20 CDK11A MIR200A SLC35E2 AGRN MTND1P23 LINC00115 CPSF3L OR4F5 SCNN1D TMEM240 NOC2L C1orf159 ANKRD65 RNF223 OR4F29 LOC100129534 WASH7P MORN1 MIR429 ATAD3C FNDC10 LOC105378592 GABRD LINC01128 UBE2J2 FAM132A LOC102725121
nsv950452	Chr.1:1106921 - 1637538 on Build GRCh38	Deletion	LOC102724312 TMEM88B CPSF3L SSU72 TTLL10-AS1 MRPL20 TTLL10 TNFRSF4 SCNN1D TMEM240 ATAD3B C1orf159 MIR6726 ACAP3 ANKRD65 PUSL1 B3GALT6 LINC01342 SDF4 MIR200B LOC148413 TNFRSF18 TAS1R3 MIB2 CDK11B CPTP CCNL2 VWA1 ATAD3A MIR429 MIR6808 DVL1 ATAD3C MIR200A FNDC10 MXRA8 UBE2J2 FAM132A MMP23B LOC107985729 MIR6727 AURKAIP1
nsv517709	Chr.1:817186 - 1275912 on Build GRCh38	Gain+Loss	LINC00115 LOC100130417 FAM87B KLHL17 TTLL10-AS1 TTLL10 TNFRSF4 PERM1 LOC105378948 NOC2L C1orf159 LOC107985728 RNF223 SAMD11 B3GALT6 LOC100288175 LINC01342 SDF4 MIR200B LOC284600 TNFRSF18 HES4 MIR429 MIR200A FAM41C PLEKHN1 LINC01128 UBE2J2 FAM132A ISG15 AGRN
nsv1160644	Chr.1:939652 - 1220663 on Build GRCh38	Deletion	TNFRSF18 KLHL17 TTLL10-AS1 HES4 TTLL10 TNFRSF4 PERM1 LOC105378948 MIR429 NOC2L C1orf159 MIR200A RNF223 SAMD11 PLEKHN1 LOC100288175 ISG15 AGRN LINC01342 SDF4 MIR200B
dgv2n67	Chr.1:877618 - 1426500 on Build GRCh38	Gain	LOC100130417 TMEM88B KLHL17 CPSF3L TTLL10-AS1 MRPL20 TTLL10 TNFRSF4 SCNN1D PERM1 LOC105378948 NOC2L C1orf159 LOC107985728 MIR6726 ACAP3 ANKRD65 PUSL1 RNF223 SAMD11 B3GALT6 LOC100288175 LINC01342 SDF4 MIR200B LOC148413 LOC284600 TNFRSF18 TAS1R3 HES4 CPTP CCNL2 MIR429 MIR6808 DVL1 MIR200A PLEKHN1 MXRA8 UBE2J2 FAM132A ISG15 MIR6727 AGRN AURKAIP1
nsv1003578	Chr.1:1068249 - 1282706 on Build GRCh38	Gain	TNFRSF18 TTLL10-AS1 TTLL10 TNFRSF4 SCNN1D LOC105378948 MIR429 C1orf159 MIR200A RNF223 B3GALT6 UBE2J2 FAM132A LINC01342 SDF4 MIR200B
nsv470680	Chr.1:1070426 - 1378635 on Build GRCh38	Loss	CPSF3L TTLL10-AS1 TTLL10 TNFRSF4 SCNN1D C1orf159 MIR6726 ACAP3 PUSL1 RNF223 B3GALT6 LINC01342 SDF4 MIR200B TNFRSF18 TAS1R3 CPTP MIR429 MIR6808 DVL1 MIR200A MXRA8 UBE2J2 FAM132A MIR6727 AURKAIP1
nsv469848	Chr.1:1146082 - 1322235 on Build GRCh38	Gain	TNFRSF18 CPSF3L TTLL10-AS1 TTLL10 TNFRSF4 SCNN1D MIR429 MIR6726 ACAP3 MIR200A PUSL1 B3GALT6 UBE2J2 FAM132A MIR6727 SDF4 MIR200B
nsv544956	Chr.1:1171093 - 1241217 on Build GRCh38	Loss	TNFRSF18 TTLL10-AS1 TTLL10 TNFRSF4 B3GALT6 SDF4

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

inflammatory response
immune response
multicellular organism development
positive regulation of B cell proliferation
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
T cell proliferation
regulation of cell proliferation
regulation of apoptotic process
positive regulation of MAPK cascade
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of transcription, DNA-templated
viral entry into host cell
positive regulation of immunoglobulin secretion
apoptotic signaling pathway

Function(s)

virus receptor activity
tumor necrosis factor-activated receptor activity