Hs03381700_cn

• Gene Symbol: CPSF3L
• Assay Reference Genome Location: Chr.1:1318810 on build GRCh38
• Cytoband: 1p36.33

Target Gene Details

• Entrez Gene ID: 54973
• Gene Name: cleavage and polyadenylation specific factor 3-like
• Gene Aliases: CPSF73L, INT11, INTS11, RC-68, RC68
• Location: Chr.1:1311585-1324687 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CPSF3L	NM_001256456.1			NP_001243385.1
	NM_001256460.1			NP_001243389.1
	NM_001256462.1			NP_001243391.1
	NM_001256463.1			NP_001243392.1
	NM_017871.5			NP_060341.2
	XM_011541647.1			XP_011539949.1
	XM_011541648.1			XP_011539950.1
	XM_011541650.1			XP_011539952.1
	XM_017001557.1			XP_016857046.1
	XM_017001558.1			XP_016857047.1
	AK021939.1			BAB13943.1
	AK022675.1	2	2315
	AK023356.1			BAB14541.1
	AK027767.1	3	1444
	AK056652.1
	AK058018.1
	AK092190.1
	AK291387.1
	AK297350.1
	AL136813.1			CAB66747.1
	BC000675.2			AAH00675.2
	BC007978.2			AAH07978.1
	BC008041.2			AAH08041.1
	BC020199.1			AAH20199.1
	CR533557.1			CAG38588.1
	DC295791.1
	DC299237.1
	DC299993.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv482937	Chr.1:10001 - 2368561 on Build GRCh38	Loss	ATAD3C MIR200B CDK11B ISG15 LOC100129534 PLEKHN1 C1orf159 LOC101928626 MIR6727 MMP23A LOC100134822 HES4 LOC100130417 LOC105378948 MIB2 LOC107985729 CDK11A ATAD3B MIR6859-1 DVL1 LOC100287934 MMP23B LOC100132287 TTLL10 FAM41C CPSF3L TNFRSF18 LOC102724312 LOC105378949 LOC102725121 GNB1 LOC100288175 LOC148413 ATAD3A TMEM52 LOC107984841 SKI MIR429 LOC105378589 MIR6723 LOC284600 CALML6 DDX11L1 SLC35E2 RNF223 FAAP20 FAM138A CCNL2 PUSL1 MIR1302-2 SLC35E2B MTND2P28 SAMD11 WASH7P FAM87B MRPL20 LOC105378591 NADK LOC105378592 PERM1 LOC100288069 PRKCZ LINC00115 MORN1 MTND1P23 UBE2J2 NOC2L TMEM88B ANKRD65 TNFRSF4 OR4F29 CFAP74 AURKAIP1 SDF4 MIR6859-2 ACAP3 CPTP LOC100133331 LOC107985728 SSU72 LINC01342 LOC100506504 OR4F16 LOC729737 TTLL10-AS1 MIR200A MIR6726 AGRN MXRA8 LINC01128 LOC105378947 KLHL17 OR4F5 TAS1R3 FNDC10 TMEM240 SCNN1D MIR6808 FAM132A B3GALT6 VWA1 GABRD
nsv544971	Chr.1:1294063 - 1351426 on Build GRCh38	Loss	MIR6727 ACAP3 MIR6726 PUSL1 TAS1R3 CPTP CPSF3L MIR6808 DVL1
nsv544969	Chr.1:1290683 - 1374597 on Build GRCh38	Loss	MIR6727 ACAP3 MIR6726 PUSL1 TAS1R3 CPTP CPSF3L SCNN1D MIR6808 MXRA8 DVL1 AURKAIP1
nsv997291	Chr.1:1306835 - 1376336 on Build GRCh38	Gain	MIR6727 ACAP3 PUSL1 TAS1R3 CPTP CPSF3L MIR6808 MXRA8 DVL1 AURKAIP1
nsv470680	Chr.1:1070426 - 1378635 on Build GRCh38	Loss	MIR200B TTLL10-AS1 MIR200A MIR6726 MIR429 MXRA8 C1orf159 MIR6727 UBE2J2 TAS1R3 RNF223 TNFRSF4 DVL1 AURKAIP1 TTLL10 SDF4 ACAP3 PUSL1 CPTP CPSF3L SCNN1D MIR6808 FAM132A B3GALT6 TNFRSF18 LINC01342
dgv6n100	Chr.1:1301750 - 1362354 on Build GRCh38	Gain+Loss	MIR6727 ACAP3 PUSL1 TAS1R3 CPTP CPSF3L MIR6808 MXRA8 DVL1
esv3584992	Chr.1:1314419 - 1330342 on Build GRCh38	Gain	CPTP CPSF3L
nsv1160788	Chr.1:1282706 - 1376336 on Build GRCh38	Deletion	MIR6727 ACAP3 MIR6726 PUSL1 TAS1R3 CPTP CPSF3L SCNN1D MIR6808 MXRA8 DVL1 AURKAIP1
nsv1160772	Chr.1:1027585 - 1333467 on Build GRCh38	Duplication	LOC100288175 MIR200B TTLL10-AS1 MIR200A MIR6726 MIR429 AGRN C1orf159 MIR6727 UBE2J2 TAS1R3 LOC105378948 RNF223 TNFRSF4 TTLL10 SDF4 ACAP3 PUSL1 CPTP CPSF3L SCNN1D FAM132A B3GALT6 TNFRSF18 LINC01342
nsv10161	Chr.1:776731 - 1777210 on Build GRCh38	Gain+Loss	ATAD3C FAM87B MRPL20 NADK MIR200B PERM1 CDK11B ISG15 PLEKHN1 LOC100288069 LINC00115 C1orf159 MIR6727 MMP23A UBE2J2 HES4 LOC100130417 LOC105378948 NOC2L MIB2 LOC107985729 CDK11A TMEM88B ATAD3B ANKRD65 TNFRSF4 DVL1 LOC100287934 MMP23B AURKAIP1 TTLL10 SDF4 ACAP3 CPTP FAM41C CPSF3L TNFRSF18 LOC107985728 LOC102724312 SSU72 LINC01342 LOC100288175 LOC148413 TTLL10-AS1 ATAD3A MIR200A MIR6726 MIR429 AGRN LOC284600 MXRA8 LINC01128 KLHL17 SLC35E2 TAS1R3 RNF223 FNDC10 CCNL2 TMEM240 PUSL1 SCNN1D MIR6808 FAM132A SLC35E2B B3GALT6 VWA1 SAMD11
esv3890636	Chr.1:1304555 - 1353203 on Build GRCh38	Loss	MIR6727 ACAP3 PUSL1 TAS1R3 CPTP CPSF3L MIR6808 MXRA8 DVL1
nsv1000169	Chr.1:1281678 - 1362354 on Build GRCh38	Gain	MIR6727 ACAP3 MIR6726 PUSL1 TAS1R3 CPTP CPSF3L SCNN1D MIR6808 MXRA8 DVL1
nsv950452	Chr.1:1106921 - 1637538 on Build GRCh38	Deletion	ATAD3C MRPL20 MIR200B LOC148413 TTLL10-AS1 ATAD3A MIR200A CDK11B MIR6726 MIR429 MXRA8 C1orf159 MIR6727 UBE2J2 TAS1R3 MIB2 LOC107985729 TMEM88B ATAD3B ANKRD65 TNFRSF4 DVL1 MMP23B AURKAIP1 FNDC10 TTLL10 SDF4 ACAP3 CCNL2 TMEM240 PUSL1 CPTP CPSF3L SCNN1D MIR6808 FAM132A B3GALT6 VWA1 TNFRSF18 LOC102724312 SSU72 LINC01342
esv2758912	Chr.1:1263940 - 1384492 on Build GRCh38	Loss	MIR6727 UBE2J2 TAS1R3 DVL1 AURKAIP1 ACAP3 MIR6726 PUSL1 CPTP CPSF3L SCNN1D MIR6808 MXRA8
dgv2n67	Chr.1:877618 - 1426500 on Build GRCh38	Gain	MRPL20 LOC100288175 MIR200B LOC148413 TTLL10-AS1 PERM1 MIR200A ISG15 MIR6726 MIR429 PLEKHN1 AGRN LOC284600 MXRA8 KLHL17 C1orf159 MIR6727 UBE2J2 HES4 LOC100130417 TAS1R3 LOC105378948 RNF223 NOC2L TMEM88B ANKRD65 TNFRSF4 DVL1 AURKAIP1 TTLL10 SDF4 ACAP3 CCNL2 PUSL1 CPTP CPSF3L SCNN1D MIR6808 FAM132A B3GALT6 TNFRSF18 LOC107985728 SAMD11 LINC01342
nsv469848	Chr.1:1146082 - 1322235 on Build GRCh38	Gain	MIR6727 UBE2J2 MIR200B TNFRSF4 TTLL10-AS1 TTLL10 SDF4 ACAP3 MIR200A MIR6726 MIR429 PUSL1 CPSF3L SCNN1D FAM132A B3GALT6 TNFRSF18

More Information

Additional Information:

For this assay, SNP(s) [rs76855900] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA processing factor

Gene Ontology Categories:

Process(es)

snRNA processing
snRNA transcription from RNA polymerase II promoter

Function(s)

protein binding
hydrolase activity