Hs04549288_cn

• Gene Symbol: GTF2B
• Assay Reference Genome Location: Chr.1:88855194 on build GRCh38
• Cytoband: 1p22.2

Target Gene Details

• Entrez Gene ID: 2959
• Gene Name: general transcription factor IIB
• Gene Aliases: TF2B, TFIIB
• Location: Chr.1:88852638-88891944 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GTF2B	NM_001514.5			NP_001505.1
	XM_011541299.1			XP_011539601.1
	AB451296.1
	AI457606.1
	AK289822.1
	BC020597.1			AAH20597.1
	M76766.1			AAA61149.1
	S44184.1			AAB23144.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv830537	Chr.1:88790384 - 88940395 on Build GRCh38	Gain	KYAT3 PKN2 GTF2B
nsv830525	Chr.1:88776863 - 88975647 on Build GRCh38	Loss	KYAT3 PKN2 GTF2B
nsv830514	Chr.1:88715143 - 88876830 on Build GRCh38	Loss	PKN2 GTF2B
dgv22n27	Chr.1:88791695 - 88894837 on Build GRCh38	Gain	PKN2 GTF2B

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

general transcription factor

Gene Ontology Categories:

Process(es)

regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
viral process
snRNA transcription from RNA polymerase II promoter
positive regulation of viral transcription

Function(s)

core promoter binding
protein binding
transcription factor binding
zinc ion binding
TBP-class protein binding
thyroid hormone receptor binding