Hs04593409_cn

• Gene Symbol: COMMD1
• Assay Reference Genome Location: Chr.2:61898794 on build GRCh38
• Cytoband: 2p15

Target Gene Details

• Entrez Gene ID: 150684
• Gene Name: copper metabolism domain containing 1
• Gene Aliases: C2orf5, MURR1
• Location: Chr.2:61888723-62136070 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
COMMD1	NM_001321781.1			NP_001308710.1
	NM_001321782.1			NP_001308711.1
	DT217730.1
	HY039942.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv582123	Chr.2:61719360 - 62324337 on Build GRCh38	Gain	MIR5192 COMMD1 FAM161A B3GNT2 CCT4
nsv582122	Chr.2:61692252 - 62020316 on Build GRCh38	Gain	COMMD1 FAM161A CCT4
nsv470467	Chr.2:61786803 - 62020316 on Build GRCh38	Gain	COMMD1 FAM161A CCT4
nsv582118	Chr.2:61431550 - 62075525 on Build GRCh38	Gain	COMMD1 USP34 FAM161A CCT4 XPO1
esv34000	Chr.2:61672382 - 62157212 on Build GRCh38	Loss	COMMD1 FAM161A CCT4
nsv1009446	Chr.2:61872503 - 61972765 on Build GRCh38	Gain	COMMD1 CCT4

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
Golgi to plasma membrane transport
protein transport
positive regulation of protein ubiquitination
negative regulation of NF-kappaB transcription factor activity
regulation of proteasomal ubiquitin-dependent protein catabolic process
plasma membrane to endosome transport
copper ion homeostasis
negative regulation of sodium ion transmembrane transport
negative regulation of protein localization to cell surface

Function(s)

copper ion binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
phosphatidylinositol-3,4,5-trisphosphate binding
identical protein binding
protein homodimerization activity
phosphatidylinositol-3,4-bisphosphate binding
phosphatidic acid binding
phosphatidylinositol-3,5-bisphosphate binding