Hs04620980_cn

• Gene Symbol: EIF4E2
• Assay Reference Genome Location: Chr.2:232551317 on build GRCh38
• Cytoband: 2q37.1

Target Gene Details

• Entrez Gene ID: 9470
• Gene Name: eukaryotic translation initiation factor 4E family member 2
• Gene Aliases: 4E-LP, 4EHP, EIF4EL3, IF4e
• Location: Chr.2:232550587-232583645 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EIF4E2	NM_001276336.1			NP_001263265.1
	NM_001276337.1			NP_001263266.1
	NM_001282958.1			NP_001269887.1
	NM_004846.3			NP_004837.1
	XM_005246975.3			XP_005247032.1
	XM_011512206.2			XP_011510508.1
	XM_017005377.1			XP_016860866.1
	AB209519.1			BAD92756.1
	AF038957.1			AAC39871.1
	AF047695.1			AAC18565.1
	AF068117.1			AAC19374.1
	AK022518.1
	AK303802.1
	BC005392.1			AAH05392.1
	BC005874.2			AAH05874.1
	BC021226.2			AAH21226.1
	BC021690.1			AAH21690.1
	BG913475.1
	CD684451.1
	DA992544.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv821918	Chr.2:232319063 - 232560965 on Build GRCh38	Gain	PRSS56 EIF4E2 ALPI ALPPL2 ECEL1P2 CHRNG ECEL1 ALPP CHRND DIS3L2 MIR5001 TIGD1
nsv3212	Chr.2:232526220 - 232564112 on Build GRCh38	Deletion	EIF4E2 CHRNG CHRND MIR5001 TIGD1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

translation factor, translation initiation factor, translational protein

Gene Ontology Categories:

Process(es)

in utero embryonic development
translational initiation
negative regulation of translation

Function(s)

RNA cap binding
translation initiation factor activity
protein binding
translation factor activity, RNA binding
ubiquitin protein ligase binding
poly(A) RNA binding