Hs05105406_cn

• Gene Symbol: EIF4EBP2
• Assay Reference Genome Location: Chr.10:70409809 on build GRCh38
• Cytoband: 10q22.1

Target Gene Details

• Entrez Gene ID: 1979
• Gene Name: eukaryotic translation initiation factor 4E binding protein 2
• Gene Aliases: 4EBP2, PHASII
• Location: Chr.10:70404105-70428618 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EIF4EBP2	NM_004096.4			NP_004087.1
	AK313724.1
	BC005057.1			AAH05057.1
	BC050633.1			AAH50633.1
	BG717474.1
	BT007317.1			AAP35981.1
	CR542240.1			CAG47036.1
	L36056.1			AAA62270.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv32737	Chr.10:69504230 - 70786847 on Build GRCh38	Gain+Loss	PPA1 AIFM2 TBATA H2AFY2 ADAMTS14 NEUROG3 C10orf35 SAR1A TYSND1 LRRC20 EIF4EBP2 NPFFR1 COL13A1 NODAL PRF1 TSPAN15 PALD1
nsv1043245	Chr.10:70290210 - 70915897 on Build GRCh38	Loss	PCBD1 TBATA EIF4EBP2 NODAL ADAMTS14 SGPL1 PRF1 PALD1 LRRC20

More Information

Additional Information:

For this assay, SNP(s) [rs114767735,rs74799670] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

translation initiation factor

Gene Ontology Categories:

Process(es)

translation
memory
insulin receptor signaling pathway
cAMP-mediated signaling
TOR signaling
social behavior
negative regulation of translational initiation
regulation of synaptic plasticity
modulation of synaptic transmission

Function(s)

protein binding
eukaryotic initiation factor 4E binding
translation repressor activity