Hs06560358_cn

• Gene Symbol: TIE1
• Assay Reference Genome Location: Chr.1:43310828 on build GRCh38
• Cytoband: 1p34.2

Target Gene Details

• Entrez Gene ID: 7075
• Gene Name: tyrosine kinase with immunoglobulin like and EGF like domains 1
• Gene Aliases: JTK14, TIE
• Location: Chr.1:43300895-43323110 on Build GRCh38
• Assay Gene Location: Within Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TIE1	NM_001253357.1			NP_001240286.1
	NM_005424.4			NP_005415.1
	XM_005271163.1			XP_005271220.1
	XM_006710869.1			XP_006710932.1
	XM_017002207.1			XP_016857696.1
	AF217976.1			AAG17219.1
	AK225560.1
	AK296735.1
	AK300399.1
	AK300623.1
	AK307639.1
	BC038239.1			AAH38239.1
	EU826590.1
	X60957.1			CAA43290.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv546128	Chr.1:43301467 - 43451738 on Build GRCh38	Loss	MIR6734 ELOVL1 MPL CDC20 MIR6735 TIE1 SZT2 MED8 HYI
nsv829693	Chr.1:43129457 - 43312977 on Build GRCh38	Loss	CFAP57 TMEM125 EBNA1BP2 FAM183A TIE1 MIR6733 C1orf210

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

angiogenesis
vasculogenesis
in utero embryonic development
signal transduction
mesoderm development
negative regulation of angiogenesis
peptidyl-tyrosine phosphorylation
negative regulation of cell migration
response to retinoic acid
plasma membrane fusion

Function(s)

transmembrane receptor protein tyrosine kinase activity
protein binding
ATP binding