Hs00302913_cn

• Gene Symbol: TBCD
• Assay Reference Genome Location: Chr.17:82832667 on build GRCh38
• Cytoband: 17q25.3

Target Gene Details

• Entrez Gene ID: 6904
• Gene Name: tubulin folding cofactor D
• Gene Aliases: SSD-1, tfcD
• Location: Chr.17:82752048-82943186 on Build GRCh38
• Assay Gene Location: Within Intron 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TBCD	NM_005993.4			NP_005984.3
	XM_005256396.4			XP_005256453.1
	XM_006722290.2			XP_006722353.1
	XM_011523589.1			XP_011521891.1
	XM_011523590.1			XP_011521892.1
	XM_011523591.1			XP_011521893.1
	XM_011523593.1			XP_011521895.1
	XM_017024987.1			XP_016880476.1
	XM_017024988.1			XP_016880477.1
	XM_017024990.1			XP_016880479.1
	AB023205.1
	AJ006417.1			CAA07022.1
	AK091959.1			BAC03777.1
	AK293471.1
	AL133562.1			CAB63716.1
	BC003094.1			AAH03094.1

Target Gene Details

• Entrez Gene ID: 79755
• Gene Name: zinc finger protein 750
• Gene Aliases: ZFP750
• Location: Chr.17:82829434-82840055 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZNF750	NM_024702.2			NP_078978.2
	AK023903.1			BAB14718.1
	AK301690.1
	BC109036.1			AAI09037.1
	BC109037.1			AAI09038.1
	DA872185.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1067553	Chr.17:82530808 - 83091923 on Build GRCh38	Loss	LOC105371944 B3GNTL1 FOXK2 TBCD ZNF750 METRNL WDR45B MIR4525 FN3KRP RAB40B LOC101929552 FN3K LOC105376791
nsv833575	Chr.17:82660876 - 82847512 on Build GRCh38	Loss	FN3KRP RAB40B TBCD ZNF750 LOC101929552 FN3K LOC105376791 MIR4525
nsv428351	Chr.17:81152631 - 83064073 on Build GRCh38	Gain	LOC105371944 B3GNTL1 TMEM105 MIR4525 LOC101929511 ARL16 ASPSCR1 SIRT7 LRRC45 OGFOD3 CCDC57 ARHGDIA LOC101929552 P4HB PPP1R27 FOXK2 MIR4740 LOC100130370 SECTM1 MRPL12 MAFG-AS1 CSNK1D RAC3 UTS2R RAB40B ACTG1 FAAP100 C17orf62 AATK-AS1 MCRIP1 GPS1 LINC00482 TBCD ZNF750 NPLOC4 SLC16A3 TEX19 DCXR PCYT2 HGS TSPAN10 FN3KRP MAFG NOTUM MIR3186 C17orf89 NPB NARF FN3K RFNG HEXDC LOC105376791 MIR6786 SLC38A10 LOC105376790 FSCN2 MYADML2 DUS1L ANAPC11 WDR45B FASN SLC25A10 STRA13 MIR6787 BAHCC1 CEP131 CD7 SNORD134 OXLD1 ALYREF PDE6G GCGR LOC105371925 TEPSIN AATK CCDC137 PYCR1
nsv1057589	Chr.17:82815790 - 82852057 on Build GRCh38	Loss	TBCD ZNF750
nsv833576	Chr.17:82769162 - 82847512 on Build GRCh38	Gain	TBCD ZNF750
esv2762577	Chr.17:82244836 - 82838431 on Build GRCh38	Gain+Loss	FOXK2 LOC105376790 TBCD ZNF750 SECTM1 TEX19 WDR45B CSNK1D MIR4525 LOC101929511 FN3KRP UTS2R CD7 RAB40B C17orf62 NARF OGFOD3 LOC101929552 FN3K HEXDC LOC105376791
esv21913	Chr.17:81828123 - 83103548 on Build GRCh38	Gain+Loss	LOC105371944 B3GNTL1 MIR4525 LOC101929511 ASPSCR1 SIRT7 LRRC45 OGFOD3 CCDC57 ARHGDIA LOC101929552 P4HB PPP1R27 FOXK2 SECTM1 METRNL MAFG-AS1 CSNK1D RAC3 UTS2R RAB40B C17orf62 MCRIP1 GPS1 TBCD ZNF750 SLC16A3 TEX19 DCXR PCYT2 FN3KRP MAFG NOTUM NPB NARF FN3K RFNG HEXDC LOC105376791 LOC105376790 MYADML2 DUS1L ANAPC11 WDR45B FASN STRA13 MIR6787 CD7 SNORD134 ALYREF PYCR1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chaperone

Gene Ontology Categories:

Process(es)

protein folding
tubulin complex assembly
post-chaperonin tubulin folding pathway
negative regulation of cell-substrate adhesion
negative regulation of microtubule polymerization
adherens junction assembly
positive regulation of GTPase activity
bicellular tight junction assembly
transcription from RNA polymerase II promoter
epidermis development
cell differentiation
positive regulation of transcription from RNA polymerase II promoter

Function(s)

GTPase activator activity
protein binding
beta-tubulin binding
chaperone binding
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
metal ion binding