Hs00515268_cn

• Gene Symbol: ALOXE3
• Assay Reference Genome Location: Chr.17:8096548 on build GRCh38
• Cytoband: 17p13.1

Target Gene Details

• Entrez Gene ID: 59344
• Gene Name: arachidonate lipoxygenase 3
• Gene Aliases: ARCI3, E-LOX, eLOX-3, eLOX3
• Location: Chr.17:8095900-8118916 on Build GRCh38
• Assay Gene Location: Within Exon 19

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ALOXE3	NM_001165960.1	16	2749	NP_001159432.1
	NM_021628.2	16	2585	NP_067641.2
	AF182218.1	15	2416	AAG16899.1
	AJ269499.1	15	2714	CAC12843.1
	AK292732.1
	AK296416.1	16	2650
	BC101938.1	15	2437	AAI01939.1
	BC101939.1	15	2437	AAI01940.1
	BC103508.1	15	2437	AAI03509.1
	BC104724.1	15	2437	AAI04725.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833352	Chr.17:8029719 - 8187575 on Build GRCh38	Loss	ALOX15B MIR6883 MIR4314 VAMP2 ALOX12B TRG-GCC2-6 MIR4521 LOC105371518 TMEM107 ALOXE3 PER1 SNORD118 HES7
nsv574334	Chr.17:8096271 - 8110990 on Build GRCh38	Loss	ALOXE3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

sphingolipid metabolic process
sensory perception of pain
arachidonic acid metabolic process
lipoxygenase pathway
peroxisome proliferator activated receptor signaling pathway
linoleic acid metabolic process
fat cell differentiation
ceramide biosynthetic process
hepoxilin biosynthetic process
oxidation-reduction process
establishment of skin barrier

Function(s)

iron ion binding
protein binding
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
lyase activity
hepoxilin A3 synthase activity