Hs00728095_cn

• Gene Symbol: USP19
• Assay Reference Genome Location: Chr.3:49111735 on build GRCh38
• Cytoband: 3p21.31

Target Gene Details

• Entrez Gene ID: 10869
• Gene Name: ubiquitin specific peptidase 19
• Gene Aliases: ZMYND9
• Location: Chr.3:49108046-49120938 on Build GRCh38
• Assay Gene Location: Within Exon 21

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
USP19	NM_001199160.1	21	3295	NP_001186089.1
	NM_001199161.1	21	3301	NP_001186090.1
	NM_001199162.1	21	3265	NP_001186091.1
	NM_006677.2	20	2992	NP_006668.1
	XM_005264823.2	21	3302	XP_005264880.1
	XM_005264824.2	21	3321	XP_005264881.1
	XM_005264825.2	21	3296	XP_005264882.1
	XM_005264826.2	21	3296	XP_005264883.1
	XM_005264827.2	21	3257	XP_005264884.1
	XM_005264829.2	21	3302	XP_005264886.1
	XM_005264830.2	20	2999	XP_005264887.1
	XM_005264831.2	20	2948	XP_005264888.1
	XM_006712946.2	21	3299	XP_006713009.1
	XM_006712947.2	21	3248	XP_006713010.1
	XM_006712948.2	21	3290	XP_006713011.1
	XM_006712949.2	21	3152	XP_006713012.1
	XM_006712950.2	21	3251	XP_006713013.1
	XM_006712951.2	21	3248	XP_006713014.1
	XM_006712952.2	21	3245	XP_006713015.1
	XM_006712953.1	21	3216	XP_006713016.1
	XM_017005615.1	21	3293	XP_016861104.1
	XM_017005616.1	21	3287	XP_016861105.1
	XM_017005617.1	21	3251	XP_016861106.1
	XM_017005618.1	21	3296	XP_016861107.1
	XM_017005619.1	21	3293	XP_016861108.1
	XM_017005620.1	21	3287	XP_016861109.1
	XM_017005621.1	21	3146	XP_016861110.1
	XM_017005622.1	21	3257	XP_016861111.1
	XM_017005623.1	21	3140	XP_016861112.1
	XM_017005624.1	21	3140	XP_016861113.1
	XM_017005625.1	20	2993	XP_016861114.1
	XM_017005626.1	20	3006	XP_016861115.1
	XM_017005627.1	20	2954	XP_016861116.1
	XM_017005628.1	20	2948	XP_016861117.1
	XM_017005629.1	20	3063	XP_016861118.1
	XM_017005630.1	20	2999	XP_016861119.1
	XM_017005631.1	20	2993	XP_016861120.1
	XM_017005632.1	20	2993	XP_016861121.1
	XM_017005633.1	20	2987	XP_016861122.1
	XM_017005634.1	20	2954	XP_016861123.1
	XM_017005635.1	14	1730	XP_016861124.1
	AB020698.1	20	2834
	AK294756.1	21	3188
	AK300425.1	21	3119
	BC048269.1	2	140	AAH48269.1
	BC065909.1	9	1072	AAH65909.1
	BC082241.1	18	2368	AAH82241.1
	BC106029.1			AAI06030.1
	BC142660.1	21	3171
	BC142727.1	21	3177
	BC146752.1	20	2834

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv834686	Chr.3:49068614 - 49233123 on Build GRCh38	Loss	QARS LAMB2 CCDC71 CCDC36 C3orf84 QRICH1 MIR6890 LAMB2P1 USP19 KLHDC8B

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

cysteine protease

Gene Ontology Categories:

Process(es)

protein deubiquitination
ER-associated ubiquitin-dependent protein catabolic process
regulation of protein stability
response to endoplasmic reticulum stress
negative regulation of skeletal muscle tissue development
protein stabilization
protein K48-linked deubiquitination
positive regulation of cell cycle process
regulation of cellular response to hypoxia
negative regulation of proteasomal protein catabolic process
regulation of ERAD pathway

Function(s)

thiol-dependent ubiquitin-specific protease activity
protein binding
ubiquitin protein ligase binding
metal ion binding
Hsp90 protein binding
Lys48-specific deubiquitinase activity