Hs01340015_cn

• Gene Symbol: CBX4
• Assay Reference Genome Location: Chr.17:79833360 on build GRCh38
• Cytoband: 17q25.3

Target Gene Details

• Entrez Gene ID: 8535
• Gene Name: chromobox 4
• Gene Aliases: NBP16, PC2
• Location: Chr.17:79833156-79839414 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CBX4	NM_003655.2	5	2445	NP_003646.2
	XM_011525399.2	3	3954	XP_011523701.1
	AI796748.1	1	211
	BC014967.1	6	1491	AAH14967.1
	EU439707.1	5	2477

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv538n67	Chr.17:79765152 - 79848648 on Build GRCh38	Gain	CBX8 CBX2 CBX4
nsv469865	Chr.17:79770348 - 79957778 on Build GRCh38	Loss	CBX8 LOC101928738 CBX2 TBC1D16 LOC101928766 CBX4
nsv828120	Chr.17:79833105 - 79842561 on Build GRCh38	Gain	CBX4
nsv828116	Chr.17:79748992 - 79855333 on Build GRCh38	Loss	CBX8 CBX2 CBX4

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
covalent chromatin modification
protein sumoylation
negative regulation of apoptotic process
negative regulation of transcription, DNA-templated

Function(s)

chromatin binding
transcription corepressor activity
single-stranded RNA binding
protein binding
ligase activity
SUMO transferase activity
enzyme binding
SUMO binding
methylated histone binding
transcription regulatory region DNA binding
phosphoprotein binding