Hs01598835_cn

• Gene Symbol: TRHDE
• Assay Reference Genome Location: Chr.12:72273466 on build GRCh38
• Cytoband: 12q21.1

Target Gene Details

• Entrez Gene ID: 29953
• Gene Name: thyrotropin releasing hormone degrading enzyme
• Gene Aliases: PAP-II, PGPEP2, TRH-DE
• Location: Chr.12:72087288-72666662 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRHDE	NM_013381.2	1	718	NP_037513.1
	XM_005268819.4	1	823	XP_005268876.1
	XM_017019243.1	1	823	XP_016874732.1
	XM_017019244.1			XP_016874733.1
	AF126372.1	1	781	AAF13141.1
	AY358765.1	1	711	AAQ89125.1
	BC142706.1	1	718
	BC150181.1	1	718

Target Gene Details

• Entrez Gene ID: 283392
• Gene Name: TRHDE antisense RNA 1
• Gene Aliases: -
• Location: Chr.12:72253507-72273509 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRHDE-AS1	NR_026836.1
	NR_026837.1
	DA024500.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832452	Chr.12:72191191 - 72370715 on Build GRCh38	Gain	TRHDE TRHDE-AS1
nsv1044083	Chr.12:72253860 - 72881746 on Build GRCh38	Gain	TRHDE TRHDE-AS1
nsv559362	Chr.12:72248004 - 72300911 on Build GRCh38	Loss	TRHDE TRHDE-AS1
esv2422452	Chr.12:72092153 - 72781801 on Build GRCh38	Duplication	TRHDE TRHDE-AS1
nsv469465	Chr.12:72262145 - 72865334 on Build GRCh38	Gain	TRHDE TRHDE-AS1

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

metalloprotease

Gene Ontology Categories:

Process(es)

proteolysis
signal transduction
cell-cell signaling
regulation of blood pressure
peptide catabolic process

Function(s)

aminopeptidase activity
zinc ion binding
peptide binding
metalloaminopeptidase activity