Hs01626512_cn

• Gene Symbol: SRGAP3
• Assay Reference Genome Location: Chr.3:8983334 on build GRCh38
• Cytoband: 3p25.3

Target Gene Details

• Entrez Gene ID: 9901
• Gene Name: SLIT-ROBO Rho GTPase activating protein 3
• Gene Aliases: ARHGAP14, MEGAP, SRGAP2, WRP
• Location: Chr.3:8980591-9362979 on Build GRCh38
• Assay Gene Location: Within Exon 32

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SRGAP3	NM_001033117.2	22	6147	NP_001028289.1
	NM_014850.3	22	6219	NP_055665.1
	XM_011534295.1	23	6234	XP_011532597.1
	XM_011534296.1	24	6351	XP_011532598.1
	XM_011534301.2	20	8063	XP_011532603.1
	XM_011534303.1	18	4959	XP_011532605.1
	XM_017007574.1	22	6557	XP_016863063.1
	XM_017007575.1	22	6485	XP_016863064.1
	XM_017007576.1	24	5726	XP_016863065.1
	XM_017007577.1	24	5665	XP_016863066.1
	XM_017007578.1	22	6585	XP_016863067.1
	XM_017007579.1	21	6225	XP_016863068.1
	AB007871.2	22	5371	BAA24841.2
	AF427144.1	22	5587	AAN07095.1
	AF464189.1	22	5675	AAN57784.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv3689	Chr.3:8967425 - 8993205 on Build GRCh38	Deletion	RAD18 SRGAP3
nsv518352	Chr.3:8905994 - 9089915 on Build GRCh38	Loss	RAD18 SRGAP3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

GTPase-activating protein

Gene Ontology Categories:

Process(es)

signal transduction
negative regulation of cell migration
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction

Function(s)

GTPase activator activity
protein binding
Rac GTPase binding