Hs01852238_cn

• Gene Symbol: DENND6B
• Assay Reference Genome Location: Chr.22:50312192 on build GRCh38
• Cytoband: 22q13.33

Target Gene Details

• Entrez Gene ID: 414918
• Gene Name: DENN domain containing 6B
• Gene Aliases: AFI1B, FAM116B
• Location: Chr.22:50309032-50327088 on Build GRCh38
• Assay Gene Location: Within Exon 21

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DENND6B	NM_001001794.3	20	1777	NP_001001794.3
	XM_005261914.3	21	1952	XP_005261971.1
	XM_011530692.2	21	1967	XP_011528994.1
	XM_011530693.2	20	1746	XP_011528995.1
	XM_017028801.1	19	1788	XP_016884290.1
	AA864612.1	1	253
	AK054743.1	17	2224
	BC031069.1	20	1777	AAH31069.1
	BM981037.1	1	245

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv955199	Chr.22:50149372 - 50320271 on Build GRCh38	Deletion	DENND6B PLXNB2 MAPK12 SELO MAPK11 PANX2 HDAC10 TRABD TUBGCP6 MOV10L1
dgv781n67	Chr.22:50153213 - 50314433 on Build GRCh38	Gain	DENND6B PLXNB2 MAPK12 SELO MAPK11 PANX2 HDAC10 TRABD TUBGCP6 MOV10L1
nsv589209	Chr.22:50284572 - 50315934 on Build GRCh38	Loss	DENND6B PLXNB2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

positive regulation of GTPase activity

Function(s)

Rab guanyl-nucleotide exchange factor activity