Hs02201554_cn

• Gene Symbol: KLRG1
• Assay Reference Genome Location: Chr.12:9153237 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 10219
• Gene Name: killer cell lectin like receptor G1
• Gene Aliases: 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE
• Location: Chr.12:8989079-9255692 on Build GRCh38
• Assay Gene Location: Within Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLRG1	XM_017018685.1			XP_016874174.1

Target Gene Details

• Entrez Gene ID: 5858
• Gene Name: PZP, alpha-2-macroglobulin like
• Gene Aliases: CPAMD6
• Location: Chr.12:9140730-9208370 on Build GRCh38
• Assay Gene Location: Within Exon 30

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PZP	NM_002864.2	30	3910	NP_002855.2
	XM_011520804.2	30	3909	XP_011519106.1
	XM_011520805.2	30	3906	XP_011519107.1
	XM_017019763.1	30	3909	XP_016875252.1
	XM_017019764.1	30	3909	XP_016875253.1
	XM_017019765.1	28	3660	XP_016875254.1
	XM_017019766.1	27	3809	XP_016875255.1
	AK313639.1	30	3909
	BC111756.1	27	3809	AAI11757.1
	X54380.1	30	3910	CAA38255.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv523958	Chr.12:9150844 - 9396476 on Build GRCh38	Loss	MIR1244-3 LINC00987 LOC642846 PZP LOC101930452 KLRG1 LOC105369649 A2MP1 LOC101928030
nsv1051530	Chr.12:8442286 - 9951690 on Build GRCh38	Gain	AICDA LOC642846 CLEC4D DDX12P CLEC4E KLRF1 LOC101928030 MIR1244-3 LOC100506159 CLEC12A MFAP5 CLEC2D LOC105369728 LOC105369649 A2MP1 CLECL1 M6PR LINC00987 PHC1 PZP CD69 LOC101930452 LOC400002 LOC374443 KLRG1 A2ML1 LINC00612 CLEC2A CLEC2B KLRF2 OVOS LOC105376678 LOC728715 A2M-AS1 KLRB1 CLEC6A A2M RIMKLB
nsv527404	Chr.12:9098005 - 9282648 on Build GRCh38	Gain	MIR1244-3 LINC00987 PZP KLRG1 A2M A2MP1

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor, protease inhibitor

Gene Ontology Categories:

Process(es)

inflammatory response
cellular defense response
cell surface receptor signaling pathway
innate immune response
female pregnancy
negative regulation of endopeptidase activity

Function(s)

receptor activity
protein binding
carbohydrate binding
endopeptidase inhibitor activity
serine-type endopeptidase inhibitor activity