Hs02628491_cn

• Gene Symbol: PRAM1
• Assay Reference Genome Location: Chr.19:8499022 on build GRCh38
• Cytoband: 19p13.2

Target Gene Details

• Entrez Gene ID: 84106
• Gene Name: PML-RARA regulated adaptor molecule 1
• Gene Aliases: PML-RAR, PRAM-1
• Location: Chr.19:8490055-8502654 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PRAM1	NM_032152.4	2	849	NP_115528.4
	XM_005272502.2	2	835	XP_005272559.1
	XM_011528352.2	2	855	XP_011526654.1
	XM_011528353.2	2	853	XP_011526655.1
	AJ272324.1	1	993	CAC17767.1
	AK308227.1	2	832
	BC028012.1	3	806	AAH28012.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv137n111	Chr.19:8488438 - 8590905 on Build GRCh38	Deletion	MYO1F ZNF414 HNRNPM PRAM1 ADAMTS10
dgv6258n54	Chr.19:8487389 - 8564616 on Build GRCh38	Loss	MYO1F ZNF414 HNRNPM PRAM1
nsv578559	Chr.19:8483291 - 8532981 on Build GRCh38	Loss	MYO1F ZNF414 HNRNPM PRAM1

More Information

Additional Information:

For this assay, SNP(s) [rs80155757] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

integrin-mediated signaling pathway
regulation of neutrophil degranulation

Function(s)

protein binding
lipid binding