Hs02687615_cn

• Gene Symbol: ALPP
• Assay Reference Genome Location: Chr.2:232378764 on build GRCh38
• Cytoband: 2q37.1

Target Gene Details

• Entrez Gene ID: 250
• Gene Name: alkaline phosphatase, placental
• Gene Aliases: ALP, PALP, PLAP, PLAP-1
• Location: Chr.2:232378534-232382889 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ALPP	NM_001632.4	1	231	NP_001623.3
	AK075432.1
	AK312931.1	1	231
	BC009647.1			AAH09647.1
	BC068501.1			AAH68501.1
	BC094743.1	1	94	AAH94743.1
	DA851165.1	1	127
	M14170.1			AAA51709.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv584679	Chr.2:232320342 - 232450598 on Build GRCh38	Gain	DIS3L2 ECEL1P2 ALPP ALPPL2
nsv482057	Chr.2:232378638 - 232382887 on Build GRCh38	Gain	ALPP
esv3594646	Chr.2:232368198 - 232411925 on Build GRCh38	Loss	ECEL1P2 ALPP ALPPL2
esv2659833	Chr.2:232338776 - 232449522 on Build GRCh38	Deletion	DIS3L2 ECEL1P2 ALPP ALPPL2
esv34493	Chr.2:232306777 - 232447741 on Build GRCh38	Gain	DIS3L2 ECEL1P2 ALPP ALPPL2
esv2760660	Chr.2:232378051 - 232409435 on Build GRCh38	Loss	ECEL1P2 ALPP ALPPL2
dgv494n27	Chr.2:232341294 - 232458467 on Build GRCh38	Gain	DIS3L2 ECEL1P2 ALPP ALPI ALPPL2
nsv438382	Chr.2:232363123 - 232387927 on Build GRCh38	Loss	ECEL1P2 ALPP
dgv4185n100	Chr.2:232363002 - 232444356 on Build GRCh38	Gain	ECEL1P2 ALPP ALPPL2
nsv522450	Chr.2:232276667 - 232522925 on Build GRCh38	Loss	ECEL1 DIS3L2 PRSS56 ECEL1P2 ALPP ALPI ALPPL2
nsv1009043	Chr.2:232368341 - 232409435 on Build GRCh38	Gain	ECEL1P2 ALPP ALPPL2
nsv821918	Chr.2:232319063 - 232560965 on Build GRCh38	Gain	EIF4E2 ECEL1 CHRNG DIS3L2 CHRND PRSS56 ECEL1P2 ALPP ALPI TIGD1 MIR5001 ALPPL2
nsv521461	Chr.2:232347151 - 232450598 on Build GRCh38	Loss	ECEL1P2 ALPP ALPPL2
esv3575339	Chr.2:232344750 - 232447202 on Build GRCh38	Gain	ECEL1P2 ALPP ALPPL2
esv2763626	Chr.2:232339649 - 232447741 on Build GRCh38	Gain+Loss	DIS3L2 ECEL1P2 ALPP ALPPL2
nsv1014226	Chr.2:232362777 - 232378950 on Build GRCh38	Gain	ALPP
nsv436293	Chr.2:232343744 - 232451520 on Build GRCh38	Deletion	DIS3L2 ECEL1P2 ALPP ALPPL2
dgv160n111	Chr.2:232328858 - 232470431 on Build GRCh38	Duplication	DIS3L2 ECEL1P2 ALPP ALPI ALPPL2
nsv518263	Chr.2:232375033 - 232444838 on Build GRCh38	Loss	ECEL1P2 ALPP ALPPL2
dgv493n27	Chr.2:232340180 - 232438423 on Build GRCh38	Loss	DIS3L2 ECEL1P2 ALPP ALPPL2
dgv4186n100	Chr.2:232377635 - 232409435 on Build GRCh38	Loss	ECEL1P2 ALPP ALPPL2
dgv7338n54	Chr.2:232367354 - 232444838 on Build GRCh38	Gain	ECEL1P2 ALPP ALPPL2
dgv7336n54	Chr.2:232336618 - 232458467 on Build GRCh38	Gain	DIS3L2 ECEL1P2 ALPP ALPI ALPPL2
dgv632e201	Chr.2:232324203 - 232449753 on Build GRCh38	Deletion	DIS3L2 ECEL1P2 ALPP ALPPL2
dgv1218e212	Chr.2:232376920 - 232415079 on Build GRCh38	Loss	ECEL1P2 ALPP ALPPL2
esv3561154	Chr.2:232378383 - 232408862 on Build GRCh38	Deletion	ECEL1P2 ALPP ALPPL2
nsv584692	Chr.2:232378254 - 232438423 on Build GRCh38	Loss	ECEL1P2 ALPP ALPPL2
dgv4183n100	Chr.2:232346988 - 232444356 on Build GRCh38	Gain+Loss	ECEL1P2 ALPP ALPPL2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphatase

Gene Ontology Categories:

Process(es)

dephosphorylation

Function(s)

magnesium ion binding
alkaline phosphatase activity
protein binding
zinc ion binding