Hs02887351_cn

• Gene Symbol: NQO1
• Assay Reference Genome Location: Chr.16:69710437 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 1728
• Gene Name: NAD(P)H quinone dehydrogenase 1
• Gene Aliases: DHQU, DIA4, DTD, NMOR1, NMORI, QR1
• Location: Chr.16:69709401-69726668 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NQO1	NM_000903.2	6	1555	NP_000894.1
	NM_001025433.1	5	1453	NP_001020604.1
	NM_001025434.1	5	1441	NP_001020605.1
	NM_001286137.1	4	1377	NP_001273066.1
	BM052991.1	1	482
	BM787983.1	1	188
	J03934.1	6	1414	AAA59940.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3892878	Chr.16:69687512 - 69844258 on Build GRCh38	Gain	NQO1 NOB1 WWP2 NFAT5
esv3638928	Chr.16:69677077 - 69756070 on Build GRCh38	Gain	NQO1 NOB1 NFAT5

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

regulation of cellular amino acid metabolic process
xenobiotic metabolic process
nitric oxide biosynthetic process
synaptic transmission, cholinergic
aging
response to nutrient
response to toxic substance
removal of superoxide radicals
response to estradiol
negative regulation of catalytic activity
positive regulation of neuron apoptotic process
response to ethanol
oxidation-reduction process

Function(s)

NAD(P)H dehydrogenase (quinone) activity
cytochrome-b5 reductase activity, acting on NAD(P)H
superoxide dismutase activity
protein binding
identical protein binding
poly(A) RNA binding