Hs03595254_cn

• Gene Symbol: IL22RA2
• Assay Reference Genome Location: Chr.6:137156578 on build GRCh38
• Cytoband: 6q23.3

Target Gene Details

• Entrez Gene ID: 116379
• Gene Name: interleukin 22 receptor subunit alpha 2
• Gene Aliases: CRF2-10, CRF2-S1, CRF2X, IL-22BP, IL-22R-alpha-2, IL-22RA2, ZCYTOR16
• Location: Chr.6:137143820-137173648 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IL22RA2	NM_052962.2			NP_443194.1
	NM_181309.1			NP_851826.1
	NM_181310.1			NP_851827.1
	AJ297262.1			CAC83097.1
	AJ313161.1			CAC85634.1
	AJ313162.1			CAC85635.1
	AY040566.1			AAK85714.1
	AY040567.1			AAK85715.1
	AY040568.1			AAK85716.1
	AY044429.1			AAK91775.1
	AY358111.1			AAQ88478.1
	AY358737.1			AAQ89097.1
	BC125167.1
	BC125168.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759473	Chr.6:137138391 - 137252201 on Build GRCh38	Loss	IL22RA2 IFNGR1
nsv470863	Chr.6:137080640 - 138014159 on Build GRCh38	Loss	LOC100507406 IL22RA2 LOC100130476 OLIG3 TNFAIP3 IFNGR1 LOC107986649 LOC102723649

More Information

Additional Information:

For this assay, SNP(s) [rs76533009] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

cytokine-mediated signaling pathway
regulation of tyrosine phosphorylation of Stat3 protein
negative regulation of inflammatory response

Function(s)

interleukin-22 binding
interleukin-22 receptor activity