Hs04577399_cn

• Gene Symbol: PDE11A
• Assay Reference Genome Location: Chr.2:177623896 on build GRCh38
• Cytoband: 2q31.2

Target Gene Details

• Entrez Gene ID: 50940
• Gene Name: phosphodiesterase 11A
• Gene Aliases: PPNAD2
• Location: Chr.2:177623249-178108339 on Build GRCh38
• Assay Gene Location: Within Exon 24

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PDE11A	NM_001077196.1	17	7132	NP_001070664.1
	NM_001077197.1	21	7662	NP_001070665.1
	NM_016953.3	20	8631	NP_058649.3
	AK127194.1	1	2410

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv583689	Chr.2:177603280 - 177645092 on Build GRCh38	Loss	PDE11A TTC30A
esv3593466	Chr.2:177618127 - 177839958 on Build GRCh38	Gain	PDE11A TTC30A LOC105373764
nsv583688	Chr.2:177562912 - 177675565 on Build GRCh38	Loss	PDE11A TTC30A LOC105373764

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphodiesterase

Gene Ontology Categories:

Process(es)

cAMP catabolic process
signal transduction
cGMP catabolic process

Function(s)

cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-AMP phosphodiesterase activity
cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
cAMP binding
cGMP binding
metal ion binding
3',5'-cyclic-GMP phosphodiesterase activity