Hs04646199_cn

• Gene Symbol: ACKR3
• Assay Reference Genome Location: Chr.2:236543353 on build GRCh38
• Cytoband: 2q37.3

Target Gene Details

• Entrez Gene ID: 57007
• Gene Name: atypical chemokine receptor 3
• Gene Aliases: CMKOR1, CXC-R7, CXCR-7, CXCR7, GPR159, RDC-1, RDC1
• Location: Chr.2:236537131-236582358 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ACKR3	XM_005246098.3			XP_005246155.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2576763	Chr.2:236542403 - 236543488 on Build GRCh38	Insertion	ACKR3
nsv1005677	Chr.2:236369512 - 236811991 on Build GRCh38	Gain	LOC105373991 ACKR3 IQCA1
nsv997438	Chr.2:236210757 - 237034862 on Build GRCh38	Gain	LOC105373991 ASB18 ACKR3 IQCA1
nsv1000252	Chr.2:235899999 - 238766417 on Build GRCh38	Loss	ESPNL ACKR3 PER2 ERFE SCLY ASB1 ASB18 RBM44 KLHL30 ILKAP LOC643387 UBE2F HES6 LINC01107 RAMP1 MLPH IQCA1 COPS8 GBX2 LRRFIP1 LOC105373958 MIR6811 LOC101927958 COL6A3 PRLH LOC105373991 LOC105373944 LOC93463 RAB17 LOC151174 TRAF3IP1 UBE2F-SCLY AGAP1
nsv834576	Chr.2:236466567 - 236654210 on Build GRCh38	Gain	LOC105373991 ACKR3 IQCA1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

angiogenesis
vasculogenesis
positive regulation of defense response to virus by host
chemotaxis
cell adhesion
G-protein coupled receptor signaling pathway
viral process
receptor internalization
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
xenophagy
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Function(s)

scavenger receptor activity
protein binding
coreceptor activity
C-X-C chemokine receptor activity
C-X-C chemokine binding