Hs05223073_cn

• Gene Symbol: DCLRE1C
• Assay Reference Genome Location: Chr.10:14905484 on build GRCh38
• Cytoband: 10p13

Target Gene Details

• Entrez Gene ID: 64421
• Gene Name: DNA cross-link repair 1C
• Gene Aliases: A-SCID, DCLREC1C, RS-SCID, SCIDA, SNM1C
• Location: Chr.10:14897853-14954432 on Build GRCh38
• Assay Gene Location: Within Exon 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DCLRE1C	NM_001033855.2	14	5425	NP_001029027.1
	NM_001033857.2	15	5510	NP_001029029.1
	NM_001033858.2	16	5832	NP_001029030.1
	NM_001289076.1	12	5284	NP_001276005.1
	NM_001289077.1	15	5556	NP_001276006.1
	NM_001289078.1	12	5317	NP_001276007.1
	NM_001289079.1	16	5878	NP_001276008.1
	NM_022487.3	13	5369	NP_071932.2
	NR_110297.1	17	5778
	XM_017016556.1			XP_016872045.1
	XM_017016559.1			XP_016872048.1
	XM_017016560.1			XP_016872049.1
	BC022254.1			AAH22254.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv469720	Chr.10:14865281 - 15037379 on Build GRCh38	Gain	MEIG1 SUV39H2 LOC105376432 LOC105376430 DCLRE1C HSPA14
nsv831793	Chr.10:14870604 - 15058763 on Build GRCh38	Loss	OLAH MEIG1 SUV39H2 LOC105376432 LOC105376430 DCLRE1C HSPA14

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

adaptive immune response
double-strand break repair via nonhomologous end joining
response to ionizing radiation
B cell differentiation
protection from non-homologous end joining at telomere
V(D)J recombination
interstrand cross-link repair
nucleic acid phosphodiester bond hydrolysis

Function(s)

single-stranded DNA endodeoxyribonuclease activity
damaged DNA binding
endonuclease activity
protein binding
5'-3' exonuclease activity
5'-3' exodeoxyribonuclease activity