Hs06222162_cn

• Gene Symbol: ERI1
• Assay Reference Genome Location: Chr.8:8898280 on build GRCh38
• Cytoband: 8p23.1

Target Gene Details

• Entrez Gene ID: 90459
• Gene Name: exoribonuclease 1
• Gene Aliases: 3'HEXO, HEXO, THEX1
• Location: Chr.8:8892225-9100262 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ERI1	XM_017013949.1			XP_016869438.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv972228	Chr.8:8895187 - 8901517 on Build GRCh38	Deletion	ERI1
nsv610190	Chr.8:8886730 - 8909371 on Build GRCh38	Loss	ERI1 MFHAS1
nsv831228	Chr.8:8750877 - 8933280 on Build GRCh38	Loss	ERI1 MFHAS1
dgv1370e214	Chr.8:8851973 - 8899115 on Build GRCh38	Gain	ERI1 MFHAS1
nsv831229	Chr.8:8894013 - 9068725 on Build GRCh38	Gain+Loss	ERI1 MIR4660
nsv1018828	Chr.8:8752370 - 8933150 on Build GRCh38	Loss	ERI1 MFHAS1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

exoribonuclease

Gene Ontology Categories:

Process(es)

exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
gene silencing by RNA
rRNA 3'-end processing
histone mRNA catabolic process

Function(s)

3'-5' exonuclease activity
rRNA binding
ribosome binding
metal ion binding
histone pre-mRNA stem-loop binding