Hs06377453_cn

• Gene Symbol: ALOX5AP
• Assay Reference Genome Location: Chr.13:30753424 on build GRCh38
• Cytoband: 13q12.3

Target Gene Details

• Entrez Gene ID: 241
• Gene Name: arachidonate 5-lipoxygenase activating protein
• Gene Aliases: FLAP
• Location: Chr.13:30713478-30764428 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ALOX5AP	NM_001204406.1			NP_001191335.1
	NM_001629.3			NP_001620.2
	XM_017020522.1			XP_016876011.1
	AK314143.1
	BC018538.1			AAH18538.1
	BG569867.1
	BQ003388.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv984	Chr.13:30747467 - 30777530 on Build GRCh38	Insertion	ALOX5AP
nsv832574	Chr.13:30657196 - 30822408 on Build GRCh38	Gain	ALOX5AP USPL1 LINC00398

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transferase

Gene Ontology Categories:

Process(es)

leukotriene metabolic process
leukotriene biosynthetic process
lipoxygenase pathway
positive regulation of catalytic activity
protein homotrimerization
cellular response to calcium ion
lipoxin metabolic process

Function(s)

glutathione transferase activity
leukotriene-C4 synthase activity
glutathione peroxidase activity
protein binding
enzyme activator activity
protein N-terminus binding
arachidonic acid binding