Hs06573429_cn

• Gene Symbol: RUNX3
• Assay Reference Genome Location: Chr.1:24911105 on build GRCh38
• Cytoband: 1p36.11

Target Gene Details

• Entrez Gene ID: 864
• Gene Name: runt related transcription factor 3
• Gene Aliases: AML2, CBFA3, PEBP2aC
• Location: Chr.1:24899511-24965158 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RUNX3	NM_001031680.2			NP_001026850.1
	NM_001320672.1			NP_001307601.1
	NM_004350.2			NP_004341.1
	XM_005246024.4			XP_005246081.1
	XM_011542351.1			XP_011540653.1
	AK300056.1
	AK301044.1
	BC013362.2			AAH13362.1
	X79550.2			CAA56093.2
	Z35278.1			CAA84541.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv508581	Chr.1:24884488 - 24968228 on Build GRCh38	Deletion	MIR6731 RUNX3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

Runt transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
ossification
chondrocyte differentiation
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
protein phosphorylation
hemopoiesis
regulation of cell differentiation
negative regulation of cell cycle
positive regulation of transcription, DNA-templated
peripheral nervous system neuron development
negative regulation of epithelial cell proliferation
response to transforming growth factor beta

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
ATP binding