Hs07141650_cn

• Gene Symbol: CNOT3
• Assay Reference Genome Location: Chr.19:54138878 on build GRCh38
• Cytoband: 19q13.42

Target Gene Details

• Entrez Gene ID: 4849
• Gene Name: CCR4-NOT transcription complex subunit 3
• Gene Aliases: LENG2, NOT3, NOT3H
• Location: Chr.19:54137689-54155708 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CNOT3	NM_014516.3			NP_055331.1
	XM_005278279.1			XP_005278336.1
	XM_005278280.2			XP_005278337.1
	XM_005278281.1			XP_005278338.1
	XM_005278282.2			XP_005278339.1
	XM_011526992.1			XP_011525294.1
	XM_011526993.2			XP_011525295.1
	AK160386.1			BAD18729.1
	AK300434.1
	BC016474.1			AAH16474.1
	BQ439042.1
	DB076207.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3644782	Chr.19:54138064 - 54154026 on Build GRCh38	Gain	CNOT3
nsv515623	Chr.19:54102901 - 54179150 on Build GRCh38	Loss	PRPF31 MBOAT7 TFPT TMC4 NDUFA3 LENG1 CNOT3
nsv953613	Chr.19:54097214 - 54198733 on Build GRCh38	Deletion	PRPF31 MBOAT7 OSCAR TFPT TMC4 NDUFA3 TSEN34 LENG1 CNOT3
esv2718812	Chr.19:53184636 - 54322450 on Build GRCh38	Deletion	VN1R4 LOC284379 MIR527 MIR520A MIR516A1 MIR520F MIR371A MIR516B2 MIR525 MIR517A MIR371B MIR935 MIR526B MIR526A2 MIR519D TMC4 MIR520D MIR523 MIR518E TSEN34 MIR518A1 MIR518C MIR518D LILRA6 LENG1 PRPF31 MIR519A2 ZNF331 LILRB5 MIR518A2 MIR519C MIR519A1 MIR515-2 TPM3P9 TARM1 NLRP12 CNOT3 MIR517C MBOAT7 MIR1283-1 MIR515-1 RPS9 LOC105372457 MIR518B MIR520E LILRA5 MIR512-2 MIR520B MIR516B1 VSTM1 MIR520C CACNG6 MIR517B PRKCG ZNF765 LILRB2 NDUFA3 MYADM FAM90A27P MIR522 OSCAR DPRX MIR1283-2 MIR373 ZNF818P MIR519E ZNF525 MIR520H MIR518F VN1R2 MIR4752 ZNF677 ZNF813 MIR521-2 CACNG8 ZNF665 MIR519B MIR1323 MIR516A2 MIR498 MIR526A1 MIR512-1 ZNF845 MIR521-1 TFPT BIRC8 MIR524 MIR372 MIR520G LILRB3 ZNF761 CACNG7
nsv2545	Chr.19:54122949 - 54142607 on Build GRCh38	Insertion	PRPF31 CNOT3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

general transcription factor

Gene Ontology Categories:

Process(es)

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
nuclear-transcribed mRNA poly(A) tail shortening
trophectodermal cell differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
negative regulation of translation
gene silencing by RNA
regulation of stem cell population maintenance

Function(s)

protein binding