Mm01196645_m1

• Gene Symbol: Chek2
• Gene Name: checkpoint kinase 2
• Gene Aliases: CHK2, Cds1, HUCDS1, Rad53
• Chromosome Location: Chr.5: 110839791 - 110874140 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Chek2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_016681.3	NP_057890.1	6 - 7	848		154
GenBank mRNA	AF086905.1	-	5 - 6	809		154
	AK044913.1	-	6 - 7	849		154
	AK170235.1	-	5 - 6	792		154
	BC056617.1	-	6 - 7	872	4977960	154

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0500001152.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Protein Kinase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Chek2

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

DNA damage checkpoint
G2/M transition of mitotic cell cycle
replicative cell aging
DNA repair
double-strand break repair
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
apoptotic process
cellular response to DNA damage stimulus
DNA damage induced protein phosphorylation
cell cycle
mitotic nuclear division
intrinsic apoptotic signaling pathway in response to DNA damage
response to gamma radiation
phosphorylation
regulation of protein catabolic process
signal transduction in response to DNA damage
cellular protein catabolic process
positive regulation of transcription, DNA-templated
protein autophosphorylation
protein stabilization
cell division
signal transduction involved in intra-S DNA damage checkpoint
mitotic spindle assembly

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
ubiquitin protein ligase binding
identical protein binding
protein homodimerization activity
metal ion binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0500009897.mm.1	TC0500001152.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500009897.mm.1	NM_016681.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500009897.mm.1	NM_016681.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0500009896.mm.1	TC0500001152.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500009896.mm.1	NM_016681.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500009896.mm.1	NM_016681.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0500009898.mm.1	TC0500001152.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500009898.mm.1	NM_016681.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500009898.mm.1	NM_016681.3	Refseq