Rn00572344_m1 Best Coverage

• Gene Symbol: Shank3
• Gene Name: SH3 and multiple ankyrin repeat domains 3
• Gene Aliases: Prosap2
• Chromosome Location: Chr.7: 130474278 - 130534679 on Build Rnor_6.0
• Species: Rat
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Shank3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_021676.1	NP_067708.1	20 - 21	2576		74
GenBank mRNA	AF133301.1	-	20 - 21	2576		74
	AF159047.1	-	15 - 16	1653		74
	AJ133120.1	-	20 - 21	2577		74

More Information

Updated Mapping Information

This assay targets the same location as RTA transcript cluster(s) TC0700001650.rn.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Recommended Assay, Rattus norvegicus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Shank3

Gene Ontology Categories:

Process(es)

MAPK cascade
embryonic epithelial tube formation
synapse assembly
learning
memory
striatal medium spiny neuron differentiation
adult behavior
negative regulation of actin filament bundle assembly
social behavior
locomotory exploration behavior
vocal learning
negative regulation of cell volume
positive regulation of long-term neuronal synaptic plasticity
brain morphogenesis
neuromuscular process controlling balance
protein oligomerization
positive regulation of synapse structural plasticity
positive regulation of synaptic transmission, glutamatergic
dendritic spine morphogenesis
positive regulation of dendritic spine development
regulation of dendritic spine morphogenesis
vocalization behavior
postsynaptic density assembly
AMPA glutamate receptor clustering
NMDA glutamate receptor clustering
guanylate kinase-associated protein clustering
regulation of long-term synaptic potentiation
positive regulation of glutamate receptor signaling pathway
regulation of long term synaptic depression
positive regulation of excitatory postsynaptic potential
regulation of grooming behavior
regulation of behavioral fear response
positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity

Function(s)

actin binding
protein binding
protein C-terminus binding
zinc ion binding
SH3 domain binding
GKAP/Homer scaffold activity
ionotropic glutamate receptor binding
identical protein binding
protein self-association
scaffold protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Agilent Whole Rat Genome Microarray 4x44K v2	A_64_P060682	-	-
Agilent Whole Rat Genome Microarray 4x44K v2	A_64_P060677	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	477109	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	617831	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	795799	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	325408	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	872957	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	320493	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	336039	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	542896	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	308984	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	682099	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	48088	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	902808	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	752384	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	648615	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	82675	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	853744	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	734086	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	888870	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	570999	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	68893	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	674382	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	438641	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	237220	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	524142	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	162891	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	613146	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	423263	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	789296	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	13559	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	967123	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	540651	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	733036	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	211954	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	1875	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	301540	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	429135	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	929929	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	841052	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	152110	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	293978	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	736026	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	715328	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	39150	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	829257	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	581463	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	612489	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	966110	-	-
Agilent SurePrint G3 Rat CGH Microarray 1x1M	53020	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	150470	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	86597	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	55479	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	58695	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	90228	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	120976	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	108677	-	-
Agilent SurePrint G3 Rat CGH Microarray 4x180K	66697	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P060677	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P060682	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P060677	-	-
Agilent Whole Rat Genome Microarray 4x44K v3	A_64_P060682	-	-
Agilent SurePrint G3 Rat GE 8x60K Microarray	A_64_P060677	-	-
Agilent SurePrint G3 Rat GE 8x60K Microarray	A_64_P060682	-	-
SurePrint G3 Rat Gene Expression Microarray G4131A	A_42_P715836	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	71020	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	32497	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	104522	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	14772	-	-
Agilent Rat Genome CGH Microarray 105A (G4436A)	43026	-	-

Array Name	Probe IDs	Targets	Target Type
Affymetrix Rat Gene 1.0 ST Array	10898624	-	-
Affymetrix Rat Gene 1.0 ST Array	10898627	-	-
Affymetrix Rat Gene 1.0 ST Array	10898639	-	-
Affymetrix Rat Gene 1.0 ST Array	10898644	-	-
Affymetrix Rat Gene 1.0 ST Array	10898631	-	-
Affymetrix Rat Gene 1.0 ST Array	10898642	-	-
Affymetrix Rat Gene 1.0 ST Array	10898640	-	-
Affymetrix Rat Gene 1.0 ST Array	10898635	-	-
Affymetrix Rat Gene 1.0 ST Array	10898632	-	-
Affymetrix Rat Gene 1.0 ST Array	10898629	-	-
Affymetrix Rat Gene 1.0 ST Array	10898630	-	-
Affymetrix Rat Gene 1.0 ST Array	10898628	-	-
Affymetrix Rat Gene 1.0 ST Array	10898646	-	-
Affymetrix Rat Gene 1.0 ST Array	10898636	-	-
Affymetrix Rat Gene 1.0 ST Array	10898625	-	-
Affymetrix Rat Gene 1.0 ST Array	10898637	-	-
Affymetrix Rat Gene 1.0 ST Array	10898623	-	-
Affymetrix Rat Gene 1.0 ST Array	10898643	-	-
Affymetrix Rat Gene 1.0 ST Array	10898638	-	-
Affymetrix Rat Gene 1.0 ST Array	10898634	-	-
Affymetrix Rat Gene 1.0 ST Array	10898641	-	-
Affymetrix Rat Gene 1.0 ST Array	10898645	-	-
Affymetrix Rat Gene 1.0 ST Array	10898633	-	-
Affymetrix Rat Gene 1.0 ST Array	10898626	-	-
Affymetrix Rat Gene 1.1 ST Array	10898622	-	-
Rat Genome 230 2.0 Array	1367658_PM_at	-	-
Rat Genome 230 2.0 Array	1367658_at	-	-
Affymetrix HT Rat Focus Array	1367658_PM_at	-	-
Affymetrix HT Rat Focus Array	1367658_at	-	-
Affymetrix Rat Clariom S Assay	PSR0700012730.rn.1	TC0700001650.rn.1	RTA TC
Rat Expression Set 230	1367658_at	-	-
Rat Expression Set 230	1367658_PM_at	-	-
Affymetrix Rat Gene 1.0 ST Array	10898622	-	-

Array Name	Probe IDs	Targets	Target Type
ABI Rat Genome Survey Microarray	21487506	-	-